Monthly Archives: January 2012

PPG technology to assess orthostatic intolerance – potential biomarker for CFS

A team of researchers from Newcastle trialled non-invasive optical multi-site photoplethysmography (PPG) technology to assess cardiovascular responses to standing as the frequent finding of autonomic dysfunction and symptoms on standing has the potential to provide a diagnostic biomarker in CFS. … Continue reading

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Increased ventricular lactate found in CFS

In this third study by researchers from New York using neuroimaging they investigated a pathophysiological model which postulated that elevations of CSF lactate in patients with CFS might be caused by increased oxidative stress, cerebral hypoperfusion and/or secondary mitochondrial dysfunction. … Continue reading

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New potential diagnostic biomarker for CFS

As autonomic nervous system dysfunction is frequently reported in CFS with orthostatic intolerance (a common symptom that can be objectively assessed), researchers from Newcastle University explored the clinical value of non-invasive optical multi-site photoplethysmography (PPG) technology to assess cardiovascular responses … Continue reading

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Accuracy of referrals to an English CFS service

Almost half (49%) of all patients referred to a specialist CFS service in London during 2007-8 did not have a diagnosis of CFS. Thirty-seven percent of referrals, screened by both a psychiatrist and a physician, were declined at the point … Continue reading

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Psychophysical distress and alexithymic traits in CFS, with and without comorbid depression

Italian researchers aimed to provide a clinical and psychometric assessment (i.e. of psychological variables such as intelligence, aptitude, and personality traits) of CFS patients with and without depressive features. Higher levels of somatic complaints were found in CFS patients than … Continue reading

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Brain Studies: Ottawa 2011 Conference Reports

A report from the IACFS/ME 2011 Conference in Ottawa includes a number of presentations on the problems in the brain or central nervous system which could play a key role in ME/CFS. Decreased basal ganglia activation in CFS subjects is … Continue reading

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Serious Barriers to Care for Children with ME/CFS

Researchers from Bristol wanted to know what factors stopped children with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis accessing care. Using self-completed assessment forms for 405 children and semi structured interviews with parents they discovered that only 19% of children were seen by … Continue reading

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MRC funds £1.6m research into CFS/ME

The Medical Research Council (MRC) has awarded more than £1.6m for research into the causes of the debilitating condition chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) The investment will fund five new projects to investigate the mechanisms and underlying biological processes involved … Continue reading

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