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Monthly Archives: April 2014
New chair for WAMES
At the recent AGM Jan Russell was elected as chair replacing Tony Thompson. After 13 years of campaigning on behalf of people in Wales it was felt that Jan had become the public face of WAMES and would lead WAMES … Continue reading
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Gwyn’s 7 day sponsored walk
Recovered ME sufferer Gwyneth Hopkins will walk round Pembrokeshire for 7 days from May 11th – 17th. She plans to start at Haverfordwest at 10am Sunday 11th May, then go around the top of Cleddau estuary to Lawrenny ,then Lydstep, … Continue reading
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Tagged Gwyn Hopkins, Pembrokeshire, sponsored walk
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Sharon’s sponsored walk for WAMES
Please sponsor me! THANK YOU! After 2 decades of being unable to, I am going to attempt to walk 5km for the Welsh Association of ME and CFS Support. A big undertaking for me. Please check out my page for … Continue reading
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Tagged Sharon Price, sponsored walk
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Low-grade inflammation has a role in the development of fatigue
Abstract BACKGROUND: Although basic research on neuroimmune interactions suggests that inflammatory processes may play a role in the development of fatigue, population-based evidence on this association is limited. This study examined whether plasma C-reactive protein (CRP) and interleukin-6 (IL-6), biomarkers … Continue reading
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Tagged biomarkers, C-reactive protein, chronic fatigue, CRP, IL6, interleukin-6, plasma C-reactive protein, SF-36, Short form Health Survey
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Hypocortisolism in CFS adolescents responds to treatment
Abstract BACKGROUND: There is accumulating evidence of hypothalamic-pituitary-adrenal (HPA) axis hypofunction in chronic fatigue syndrome (CFS). However, knowledge of this hypofunction has so far come exclusively from research in adulthood, and its clinical significance remains unclear. The objective of the … Continue reading
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Tagged cortisol, HPA axis hypofunction, hypocortisolism, hypothalamic-pituitary-adrenal axis hypofunction
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Review of biomarkers in CFS
Abstract Chronic fatigue syndrome (CFS) remains an incompletely characterized illness, in part due to controversy regarding its definition, biological basis, and diagnosis. Biomarkers are objective measures that may lead to improvements in our understanding of CFS by providing a more … Continue reading
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Tagged biomarkers, phenotypes, Prof Leonard Jason, subgroups
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Post-exertional symptom exacerbation follows mental effort in ME/CFS
Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating, long-term condition characterised by extreme fatigue (worsened by exertion), muscle and joint pain, and sleep disturbance. Post-exertional fatigue has been demonstrated previously following physical exercise, but not from mental exertion … Continue reading
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Tagged cognitive effort, HADS, Hospital Anxiety and Depression Scale, MFI scales, Multidimensional Fatigue Inventory, post-exertional fatigue
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Mitochondrial dysfunction and fatigue review
Abstract Fatigue is often described by patients as a lack of energy, mental or physical tiredness, diminished endurance, and prolonged recovery after physical activity. Etiologic mechanisms underlying fatigue are not well understood; however, fatigue is a hallmark symptom of mitochondrial … Continue reading
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Tagged ATP, carnitine, Coenzyme Q10, fatigue, mitochondrial dysfunction
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Review of the role of T cells in the ME/CFS immune system
Abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a multifactorial disorder defined by symptom-specific criteria and characterised by severe and prolonged fatigue. CFS/ME typically affects a variety of bodily systems, including the immune system. Patients with CFS/ME exhibit significantly reduced Natural … Continue reading
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Tagged immune system, Natural Killer cells, NK cells, T-cells
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Cardiac dysfunction with a small heart is related to ME
Abstract The etiology of chronic fatigue syndrome (CFS) is unknown. Myalgic encephalomyelitis (ME) has been recently postulated to be the cause of CFS. Orthostatic intolerance (OI) has been known as an important symptom in predicting quality of life in CFS … Continue reading
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Tagged cardiac dysfunction, left ventricular dimensions, OI, orthostatic intolerance, small heart
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