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Norwegian rituximab trial reports negative results
The Norwegian Rituximab trial reports negative results ahead of the publication of the full results. Attempts are now under way to determine the best way forward in understanding what has been learned and how to find out which patients may still benefit from … Continue reading
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Tagged B-cell, Cort Johnson, Cyclophosphamide, Dr Oystein Fluge, Prof Olav Mella, rituximab, Simmaron Research
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New rituximab trial results from Norway
Research abstract: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We have previously suggested clinical benefit from B-cell depletion using the monoclonal anti-CD20 antibody rituximab in a randomized and placebo-controlled study. Prolonged responses were then demonstrated in … Continue reading
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Tagged B-cell, Dr Oystein Fluge, Norway, Prof Olav Mella, rituximab, T-cell
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UK rituximab trial fundraising total almost reached
Invest in ME has announced the latest fundraising total for the rituximab/B-cell research, which is a great boost as the research team at UCL are about to visit and discuss the subject with Dr Fluge and Professor Mella in Haukeland University Hospital, … Continue reading
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Tagged B-cell, Dr Oystein Fluge, IiME, Invest in ME, Prof Olav Mella, rituximab, UCL, University College London
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Rituximab leads to B-cell depletion and remission in ME/CFS
Research abstract: Background: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We previously reported a pilot case series followed by a small, randomized, placebo-controlled phase II study, suggesting that B-cell depletion using the monoclonal anti-CD20 antibody rituximab … Continue reading
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Tagged antibodies, B-cell, Dr Olav Mella, Dr Oystein Fluge, New Scientist, rituximab
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T & NK cell screening is a possible biomarker for CFS
Research abstract Background: Chronic Fatigue Syndrome (CFS) is a debilitating neuro-immune disorder of unknown etiology diagnosed by an array of clinical manifestations. Although several immunological abnormalities have been described in CFS, their heterogeneity has limited diagnostic applicability. Methods: Immunological features … Continue reading
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Tagged B-cell, immunological dysfunction, NK-cell, T-cell
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