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Brain abnormalities in ME/CFS
Brain abnormalities in myalgic encephalomyelitis/chronic fatigue syndrome: Evaluation by diffusional kurtosis imaging and neurite orientation dispersion and density imaging, by Kimura Y, Sato N, Ota M, Shigemoto Y, Morimoto E, Enokizono M, Matsuda H, Shin I, Amano K, Ono H, Sato W, Yamamura T in Journal … Continue reading
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Tagged brain dysfunction, brain inflammation, Diffusional kurtosis imaging, DKI, MRI, N Sato, NODDI, T Yamamura, Y Kimura, Yasuyoshi Watanabe
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Brain & spinal fluid abnormalities in CFS are not affected by psychiatric comorbidity
Research highlights: As a group, CFS patients have higher brain ventricular lactate, more abnormal spinal fluid results, lower brain GSH, and reduced cerebral blood flow relative to healthy sedentary controls Psychiatric comorbidity does not influence any of these potential biological … Continue reading
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Tagged brain dysfunction, brain ventricular lactate, cerebral blood flow, comorbidity, cortical glutathione, Dikoma C Shungu, Dr Benjamin Natelson, Dr Gudrun Lange, neuropsychiatric, spinal fluid protein, white cell count
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Neural consequences of PEM in ME/CFS
Research abstract: Highlights: Acute exercise affects symptoms, cognitive performance and brain function in ME/CFS. Symptom provocation by exercise is a useful model to study post-exertion malaise. Objective neurophysiological evidence of the phenomenon of post-exertion malaise. Post exertion malaise is one … Continue reading
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Tagged Alan R Light, brain dysfunction, cognitive dysfunction, Dr Dane B Cook, Dr Suzanne Vernon, fMRI, Kathleen C Light, PEM, Post-exertional malaise
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Brain scan shows altered connectivity between different regions of the brain in CFS
Research abstract: Studies using arterial spin labelling (ASL) have shown that individuals with chronic fatigue syndrome (CFS) have decreased regional cerebral blood flow, which may be associated with changes in functional neural networks. Indeed, recent studies indicate disruptions in functional … Continue reading
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Tagged brain dysfunction, fMRI, Functional connectivity
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Six year study of abnormal brain changes in ME/CFS
ME Australia blog post, by Sasha Nimmo, 12 July 2016: Six year study of abnormal brain changes in chronic fatigue syndrome patients An Australian six year study evaluating progressive brain changes associated with chronic fatigue syndrome (Fukuda and Canadian Consensus … Continue reading
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Tagged Australia, brain dysfunction, Dr Sonya Marshall-Gradisnik, Magnetic Resonance Imaging, MRI, Sasha Nimmo, white matter
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Brain white matter abnormalities in ME/CFS
ME Research UK research article, by Dr Neil Abbot, 25 May 2016: White matter abnormalities Most studies in ME/CFS are cross-sectional in nature – researchers look at patients and controls at one point in time and make comparisons between the … Continue reading
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Tagged brain dysfunction, Dr Neil Abbot, ME Research UK, white matter
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Progressive brain changes in patients with CFS
Research abstract: PURPOSE: To examine progressive brain changes associated with chronic fatigue syndrome (CFS). MATERIALS AND METHODS: We investigated progressive brain changes with longitudinal MRI in 15 CFS and 10 normal controls (NCs) scanned twice 6 years apart on the same … Continue reading
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Tagged brain dysfunction, Dr Sonya Marshall-Gradisnik, inferior fronto-occipital fasciculus, Magnetic Resonance Imaging, MRI, white matter, ZY Shan
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