Tag Archives: case definitions

The development of the DePaul symptom questionnaire: original, expanded, brief & pediatric versions

The development of the DePaul symptom questionnaire: Original, expanded, brief and pediatric versions, by Leonard A Jason, Madison Sunnquist in Frontiers in Pediatrics, 6 Nov 2018 One of the key requirements of a reliable case definition is the use of standardized procedures for assessing … Continue reading

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Operationalizing substantial reduction in functioning among young adults with CFS

Research abstract: Operationalizing Substantial Reduction in Functioning Among Young Adults with Chronic Fatigue Syndrome, by Kristen D. Gleason, Jamie Stoothoff, Damani McClellan, Sttephanie McManimen, Taylor Thorpe, Ben Z. Katz, Leonard A. Jason in International Journal of Behavioral Medicine 2018 pp1-8 [Published online 5 June 2018] Purpose: Chronic fatigue syndrome and myalgic … Continue reading

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ME, CFS & SEID: three distinct clinical entities?

Article abstract: Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, and Systemic Exertion Intolerance Disease: Three Distinct Clinical Entities, by Frank N M Twisk in Open Access Challenges 2018, 9(1), 19 [Published: 13 April 2018] Many researchers consider chronic fatigue syndrome (CFS) to be a synonym … Continue reading

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A comparison of case definitions for ME & CFS

Research abstract: A Comparison of Case Definitions for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome, by Madison Sunnquist, Leonard A Jason, P Nehrke, Ellken M Goudsmit in Chronic Dis Manag. 2017;2(2). pii: 1013. Epub 2017 May 21 Many professionals have described the … Continue reading

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Scientific progress stumbles without a valid case definition

OUP blog post, by Leonard A. Jason, August 20th 2017: Scientific progress stumbles without a valid case definition Current estimates from the Centers for Disease Control and Prevention (CDC) of the number of people in the United States with chronic … Continue reading

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Is SEID comparable to research case definitions of CFS?

Two groups of American researchers debate the appropriateness of using case definitions for research purposes. Article abstract: Mistaken conclusions about systemic exercise intolerance disease being comparable to research case definitions of CFS: a rebuttal to Chu et al., by Leonard A. Jason, Madison Sunnquist, Kristen … Continue reading

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Video lecture on clinical case definitions by Prof Jason

Youtube video published 17 March 2017: Leonard Jason’s Presentation on Case Definitions to European Network The issue of research and clinical case definitions were discussed in this 30 min March 2-017 talk, and then the European scientists asked questions for the remaining 30 … Continue reading

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Standard research criteria would aid ME/CFS research

Research abstract: Background: The Institute of Medicine (IOM) recently developed clinical criteria for what had been known as chronic fatigue syndrome. Given the broad nature of the clinical IOM criteria, there is a need for a research definition that would … Continue reading

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Differing case definitions point to the need for an accurate diagnosis of ME/CFS

Research article: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterised by unexplained and persistent or recurrent incapacitating fatigue accompanied by a variety of symptoms and substantial reductions in previous levels of occupational, educational, social and/or personal activity [1,2]. Given the absence … Continue reading

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Developing case definitions for ME and CFS using practical experience and consensus

Research abstract: Background: There has been considerable controversy regarding how to name and define the illnesses known as myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). The Institute of Medicine (IOM) report has proposed new clinical criteria and a new name for this … Continue reading

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