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Research: Endothelial cell function in Post-COVID-19 patients, with & without ME/CFS
Serum of Post-COVID-19 Syndrome patients with or without ME/CFS differentially affects endothelial cell function in vitro The endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular … Continue reading
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Tagged AECA, angiogenesis, anti-endothelial cell autoantibodies, Carmen Scheibenbogen, Claudia Kedor, Constanze Roubal, cytokines, endothelial cells, Franziska Sotzny, Lavinia Flaskamp, long Covid, Martina Seifert, Post-COVID, Sandra Bauer, Steven Uddin
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Research: Predictors for developing severe ME/CFS following infectious Mononucleosis
Predictors for developing severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome following infectious Mononucleosis, by Leonard A Jason, Joseph Cotler, Mohammed F Islam, Jacob Furst, Ben Z Katz in Journal of Rehabilitation Therapy, 2022;4(1):1-5, February 21, 2022 Research abstract: Background: About 10% … Continue reading
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Tagged Ben Z Katz, cytokines, Infectious mononucleosis, Jacob Furst, Joseph Cotler, Mohammed F Islam, Prof Leonard Jason, severe ME
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Hypothesis: Circadian rhythm disruption in ME/CFS: implications for the post-acute sequelae of COVID-19
Circadian rhythm disruption in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for the post-acute sequelae of COVID-19, by Michael J McCarthy in Brain, Behavior, & Immunity – Health, Vol 20, March 2022, [doi.org/10.1016/j.bbih.2022.100412] Highlights Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is characterized … Continue reading
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Tagged circadian rhythm, cytokines, Michael J McCarthy, PASC, Post-acute Sequelae of COVID-19, sleep disturbance, TGF-β, Transforming Growth Factor-beta
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Risks for developing ME/CFS in college students following infectious mononucleosis
Risks for developing ME/CFS in college students following infectious mononucleosis: a prospective cohort study, Leonard A Jason, PhD, Joseph Cotler, PhD, Mohammed F Islam, PhD, Madison Sunnquist, PhD, Ben Z Katz, MD in Clinical Infectious Diseases, [doi.org/10.1093/cid/ciaa1886] 25 Dec 2020 … Continue reading
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Tagged Ben Z Katz, cytokines, depression, illness behaviour, Infectious mononucleosis, Joseph Cotler, Madison L Sunnquist, Mohammed F Islam, Prof Leonard Jason, psychological distress, students
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Cytokine profiling of extracellular vesicles isolated from plasma in ME/CFS
Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/ chronic fatigue syndrome: a pilot study, by Ludovic Giloteaux, Adam O’Neal, Jesús Castro-Marrero, Susan M Levine, Maureen R Hanson in J Transl Med. 2020 Oct 12;18(1):387 [doi: 10.1186/s12967-020-02560-0] Research … Continue reading
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Tagged Adam O'Neal, cytokines, Dr Susan Levine, extracellular vesicles, immune dysfunction, Jesús Castro-Marrero, Ludovic Giloteaux, Prof Maureen Hanson
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Achieving symptom relief in patients with ME by targeting the neuro-immune interface & inducing disease tolerance
Achieving symptom relief in patients with Myalgic encephalomyelitis by targeting the neuro-immune interface and inducing disease tolerance, by Lucie ST Rodriguez, Christian Pou, Lakshmikanth Tadepally, Jingdian Zhang, Constantin Habimana Mugabo, Jun Wang, Jaromir Mikes, Axel Olin, Yang Chen, Joanna Rorbach, … Continue reading
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Tagged Axel Olin, Christian Pou, Constantin Habimana Mugabo, cytokines, IL-17 axis, INMEST, Interleukin 17, intranasal mechanical stimulation, Jan-Erik Juto, Jaromir Mikes, Jingdian Zhang, Joanna Rorbach, Jun Wang, Lakshmikanth Tadepally, Lucie ST Rodriguez, Per Julin, Petter Brodin, Tadepally Lakshmikanth, Tie-Qiang Li, vagus nerve stimulation, Yang Chen
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MCP-1 is increased in patients with CFS & FM, whilst several other immune markers are significantly lower than healthy controls
MCP-1 is increased in patients with CFS and FM, whilst several other immune markers are significantly lower than healthy controls, by Nina Groven, Egil Andreas Fors, Astrid Kamilla Stunes, Solveig Klæbo Reitan in Brain, Behavior, & Immunity – Health Vol … Continue reading
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Tagged Astrid Kamilla Stunes, CCL2, chemokines, cytokines, Egil Andreas Fors, IL-10, IL-1β, Il-4, IL-6, IL17, inflammation, interferon gamma, interleukins, MCP-1, Monocyte Chemoattractant Protein, Nina Groven, Solveig Klæbo Reitan, TGF-β1, TGF-β2, TGF-β3, TNF-α
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Shared microglial mechanisms underpinning depression & CFS & their comorbidities
Shared microglial mechanisms underpinning depression and chronic fatigue syndrome and their comorbidities, by Adriano José Maia Chaves-Filho, Danielle S Macedo, David Freitas de Lucena, Michael Maes in Behavioural Brain Research Vol 372, 17 October 2019, 111975 [https://doi.org/10.1016/j.bbr.2019.111975] Research abstract: … Continue reading
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Tagged Adriano José Maia Chaves-Filho, cytokines, Danielle S Macedo, David Freitas de Lucena, depression, Michael Maes, microglia, neuro-immune dysregulation, oxidative stress
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Towards a biomarker: Rethinking ME/CFS diagnostic reference intervals via machine learning, & the utility of activin B for defining symptom severity
Rethinking ME/CFS diagnostic reference intervals via machine learning, and the utility of activin B for defining symptom severity, by Brett A. Lidbury, Badia Kita, Alice M Richardson, Donald P Lewis, Edwina Privitera, Susan Hayward, David de Kretser and Mark Hedger … Continue reading
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Tagged Alice M Richardson, Badia Kita, biomarker, cytokines, David de Kretser, diagnosis, Donald P. Lewis, Edwina Privitera, illness severity, Mark Hedger, Prof Brett Lidbury, serum activin B, Susan Hayward
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