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Tag Archives: Dr Samantha Johnston
Reduced glycolytic reserve in isolated natural killer cells from ME/CFS patients
Reduced glycolytic reserve in isolated natural killer cells from Myalgic encephalomyelitis/ chronic fatigue syndrome patients: A preliminary investigation, by Thao Nguyen, D Staines, S Johnston, S Marshall-Gradisnik in Asian Pac J Allergy Immunol. 2018 Jul 8. [Epub ahead of print] … Continue reading
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Tagged ATP, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, glycolitic reserve, Natural Killer cells, NK cells, Prof Donald Staines, T Nguyen
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Investigation of mast cell toll-like receptor 3 in CFS/ME
Research abstract: Investigation of mast cell toll-like receptor 3 in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Systemic Mastocytosis participants using the novel application of autoMACS magnetic separation and flow cytometry, by C Balinas, T Nguyen, S Johnston, P Smith, D Staines, S Marshall-Gradisnik in Asian … Continue reading
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Tagged C Balinas, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, immune dysfunction, mast cells, MCPs, P Smith, Prof Donald Staines, T Nguyen, TLR3, toll-like receptors, white blood cells
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Australian researchers discover abnormalities in immune cell receptors in ME/CFS
Huffington Post Australia, by Luke Cooper, 22 Feb 2017: Queensland Scientists Make Chronic Fatigue Syndrome Research Breakthrough The condition has been linked to abnormal immune system cells. Queensland scientists have linked Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis … Continue reading
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Tagged Dr Samantha Johnston, Dr Sonja Marshall Gradisnik, Fiona McDonald, Huffington Post, immune cell receptors, impaired calcium mobilisation, L Clarke, Luke Cooper, Natural Killer cells, P Smith, Prof Donald Staines, Sciece alert, T Nguyen
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Review of dietary & nutrition interventions for CFS/ME
Review abstract: Background: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is characterised by unexplained fatigue for at least 6 months accompanied by a diverse but consistent set of symptoms. Diet modification and nutritional supplements could be used to improve patient outcomes, such … Continue reading
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Tagged Ansel Collatz, dietary intervention, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, N Campagnolo, Prof Donald Staines, supplements
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Australian researchers get £2.35 million to create ME/CFS diagnostic test
Griffith University press release, by Louise Durack, 1 Dec 2016: $4m grant to aid Chronic Fatigue Syndrome diagnosis Major improvements in the diagnosis of Chronic Fatigue Syndrome are expected following the awarding of $4 million [£2.35 million] in funding to one … Continue reading
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Tagged Australia, biomarkers, diagnostic test, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, Griffith University, Prof Donald Staines
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A targeted genome association study examining transient receptor potential ion channels, acetylcholine receptors, and adrenergic receptors
Research abstract: BACKGROUND: Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (CFS/ME) is a debilitating condition of unknown aetiology. It is characterized by a range of physiological effects including neurological, sensory and motor disturbances. This study examined candidate genes for … Continue reading
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Tagged adrenergic receptors, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, Prof Donald Staines, single nucleotide polymorphisms, SNPs
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B cell functional changes & Ca2+dysregulation in ME/CFS
Research abstract: Single nucleotide polymorphisms and genotypes of transient receptor potential ion channel and acetylcholine receptor genes from isolated B lymphocytes in myalgic encephalomyelitis/chronic fatigue syndrome patients, by Marshall-Gradisnik S, Johnston S , Chacko A , Nguyen T , Smith … Continue reading
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Tagged acetylcholine, Anu Chacko, B lymphocytes, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, ion channel signalling, P Smith, Prof Donald Staines, single nucleotide polymorphisms, T Nguyen
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Calcium mobilisation in natural killer cells & cell cytotoxicity in CFS/ME
Research abstract: Transient receptor potential melastatin subfamily 3 (TRPM3) ion channels play a role in calcium (Ca2+ ) cell signalling. Reduced TRPM3 has been identified in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) patients. However, the significance of TRPM3 and association with … Continue reading
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Tagged cell cytotoxicity, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, L Clarke, Natural Killer cells, NK cells, P Smith, Prof Donald Staines, T Nguyen, TRPM3 genes
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Dysregulation of protein kinase gene expression in NK Cells in CFS
Research abstract: BACKGROUND: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading
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Tagged Anu Chacko, Dr Samantha Johnston, Dr Sonja Marshall Gradisnik, Natural Killer cells, NK cells, Prof Donald Staines, protein kinase genes
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