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Research review: COVID-19 & CFS: an endocrine perspective
COVID-19 and Chronic Fatigue Syndrome: An endocrine perspective, by Rashika Bansal, Sriram Gubbi, Christian A Koch in Journal of Clinical & Translational Endocrinology 3 Dec 2021 [doi.org/10.1016/j.jcte.2021.100284] Research abstract: Patients recovering from COVID-19 may have persistent debilitating symptoms requiring … Continue reading
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Tagged adrenal function, Christian A Koch, endocrine dysregulation, HPA axis functioning, hypothalamo-pituitary-adrenal axis, Rashika Bansal, Sriram Gubbi
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Reduction of glucocorticoid receptor function in CFS – no causal link to childhood trauma
Research abstract: Reduction of glucocorticoid receptor function in CFS, by Megan Lynn, Laura Maclachlan, Andreas Finkelmeyer, James Clark, James Locke, Stephen Todryk, Wan-Fai Ng, Julia L Newton, Stuart Watson in Mediators of Inflammation [Preprint April 20, 2018] Glucocorticoid receptor (GR) function may … Continue reading
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Tagged cortisol, endocrine dysregulation, glucocorticoid receptor, James Clark, James Locke, Laura Maclachlan, Megan Lynn, Prof Andreas Finkelmeyer, Prof Julia Newton, Sjogren's syndrome, Stephen Todryk, Stuart Watson, Wan-Fai Ng
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Altered neuroendocrine control in adolescent CFS
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is a common and disabling disorder, and a major threat against adolescent health. The pathophysiology is unknown, but alteration of neuroendocrine control systems might be a central element, resulting in attenuation of the … Continue reading
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Tagged adolescents, endocrine dysregulation, hormones, HPA axis functioning, teenagers
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ME/CFS – not simply chronic fatigue but multisystem disorder
Research abstract: BACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, chronic illness that is often disabling. This paper introduces the Chronic Fatigue Initiative, which conducted a large multi-center study to more fully characterize ME/CFS and ultimately to describe and … Continue reading
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Tagged autonomic dysfunction, chronic fatigue, Chronic Fatigue Initiative, cognitive dysfunction, Dr Lucinda bateman, endocrine dysregulation, gastrointestinal disorder, inflammtory symptoms, multisystem disorder, Nancy Klimas, neuro-inflammatory symptoms, pain, Prof Anthony Komaroff, Prof Maddy Hornig
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Could use of stress management skills improve PEM?
Research abstract Chronic Fatigue Syndrome (CFS) is characterized in part by debilitating fatigue typically exacerbated by cognitive and/or physical exertion, referred to as post-exertional malaise (PEM). In a variety of populations, the cortisol awakening response (CAR) has stood out as … Continue reading
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Tagged CAR, Cort Johnson, Cortisol Awakening Response, Daniel L Hall, endocrine dysregulation, HPA axis functioning, PEM, perceived stress management skills, Post-exertional malaise, PSMS
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Relationship between insomnia and CFS/ME
Research abstract Fatigue is common in the general population, and is the hallmark of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). Although the occurrence of sleep difficulties is known to be common in subjects with fatigue, research on insomnia in such subjects … Continue reading
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Tagged cortisol, endocrine dysregulation, HPA axis functioning, insomnia, sleep
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