Tag Archives: energy metabolism

Evidence of clinical pathology abnormalities in people with ME/CFS…

Evidence of clinical pathology abnormalities in people with Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) from an analytic cross-sectional study, by Luis Nacul, Barbara de Barros, Caroline C Kingdon, Jacqueline M Cliff, Taane G Clark, Kathleen Mudie, Hazel M Dockrell, Eliana … Continue reading

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CD24 expression & B cell maturation shows a novel link with energy metabolism: potential implications for patients with ME/CFS

CD24 expression and B cell maturation shows a novel link with energy metabolism: potential implications for patients with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome , by Fane K. Mensah, Christopher W Armstrong, Venkat Reddy, Amolak S Bansal, Saul Berkovitz, Maria Leandro … Continue reading

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Infection elicited autoimmunity & ME/CFS: an explanatory model

Hypothesis and Theory article: Infection elicited autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: an explanatory model, by Jonas Blomberg, Carl-Gerhard Gottfries, Amal Elfaitouri, Muhammad Rizwan and Anders Rosén in Front. Immunol., 15 February 2018 Myalgic encephalomyelitis (ME) often also called chronic fatigue … Continue reading

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Inflammation correlates with symptoms in CFS

Research overview abstract: Inflammation correlates with symptoms in chronic fatigue syndrome, by Anthony L Komaroff in PNAS August 15, 2017 It is not unusual for patients who say they are sick to have normal results on standard laboratory testing. The physician … Continue reading

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The Stanford Paradox: elevated energy production found in ME/CFS

Health rising blog post, by Cort Johnson, 18 April 2017: The Stanford Paradox: Elevated Energy Production Found in Chronic Fatigue Syndrome (ME/CFS)   Producing energy is a big problem in Chronic Fatigue Syndrome (ME/CFS). In fact it’s probably the problem in … Continue reading

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Metabolic switch may bring on CFS

New Scientist article, by Andy Coghlan, 13 February 2016: Metabolic switch may bring on chronic fatigue syndrome It’s as if a switch has been flicked. Evidence is mounting that chronic fatigue syndrome (CFS) is caused by the body swapping to … Continue reading

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Myhill & McLaren-Howard discuss apparent contradictions in mitochondria research

DoctorMyhill.co.uk article, by Dr Sarah Myhill & John Howard-McLaren-Howard, 11 January 2017: Reply to Lawson Paper Background: In 2016, Nick Lawson, Chung-Han Hsieh, Dana March, Xinnan Wang published a paper with the title “Elevated Energy Production in Chronic Fatigue Syndrome … Continue reading

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The association of fecal microbiota & fecal, blood serum & urine metabolites in ME/CFS

Research abstract: INTRODUCTION: The human gut microbiota has the ability to modulate host metabolism. Metabolic profiling of the microbiota and the host biofluids may determine associations significant of a host–microbe relationship. Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a long-term disorder … Continue reading

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The role of lactate in ME/CFS & FM

Cort Johnson asks: Lactate – Is it Everywhere in Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?, 1 March 2016 Lactate (L-lactate) is an organic compound produced during anaerobic energy metabolism.  It’s constantly being formed – even when we are at rest … Continue reading

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Oxidative phosphorylation & lactic acid excretion are impaired in severe ME

Case study abstract: Background: In this study the muscle bioenergetic function in response to exercise in severe ME was explored to see if the underlying metabolic problem in ME, responsible for the severe difficulties with trivial exercise, and the severe loss … Continue reading

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