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ME/CFS – Metabolic disease or disturbed homeostasis?

Posted on August 16, 2018 by wames

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-Metabolic Disease or Disturbed Homeostasis? by Erifili Hatziagelaki, Maria Adamaki, Irene Tsilioni, George Dimitriadis and Theoharis C Theoharides in Journal of Pharmacology and Experimental Therapeutics August 3, 2018, jpet.118.250845 Research article abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex disease characterized by debilitating fatigue, lasting … Continue reading →

Posted in News | Tagged disturbed homeostasis, Erifili Hatziagelaki, George Dimitriadis, inflammation, Irene Tsilioni, Maria Adamaki, mast cells, metabolism, Theoharis C Theoharides | Leave a comment

The putative role of oxidative & inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders

Posted on May 22, 2018 by wames

Review summary: The putative role of oxidative stress and inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders: Focus on chronic fatigue syndrome, bipolar disorder and multiple sclerosis, by Gerwyn Morris, Brendon Stubbs, Cristiano A Köhlerx, Ken Walder, Anastasiya Slyepchenko, … Continue reading →

Posted in News | Tagged bipolar disorder, inflammation, MS, Multiple Sclerosis, oxidative stress, sleep | Comments Off

The high costs of low-grade inflammation

Posted on May 18, 2018 by wames

Review abstract: The High Costs of Low-Grade Inflammation: Persistent Fatigue as a Consequence of Reduced Cellular-Energy Availability and Non-adaptive Energy Expenditure. by Tamara E. Lacourt, Elisabeth G. Vichaya, Gabriel S. Chiu, Robert Dantzer and Cobi J. Heijnen in Front Behav Neurosci. … Continue reading →

Posted in News | Tagged cancer-related fatigue, chronic fatigue, Cobi J Heijnen, Elisabeth G Vichaya, energy, Gabriel S Chiu, inflammation, Robert Dantzer, Tamara E Lacourt | Comments Off

Inflammation correlates with symptoms in CFS

Posted on August 18, 2017 by wames

Research overview abstract: Inflammation correlates with symptoms in chronic fatigue syndrome, by Anthony L Komaroff in PNAS August 15, 2017 It is not unusual for patients who say they are sick to have normal results on standard laboratory testing. The physician … Continue reading →

Posted in News | Tagged ANS, autonomic nervous system, Central Nervous System, CNS, energy metabolism, inflammation, nitrosative stress, oxidative stress, Prof Anthony Komaroff | Comments Off

ME/CFS: A new explanation – and cure from Dr Willy Eriksen?

Posted on June 26, 2017 by wames

Tracy Duvall blog post, 10 June 2017: ME/CFS: A new explanation – and cure? In a recent paper, Dr. Willy Eriksen proposes a complete explanation for the development, diversity, and persistence of myalgic encephalomyelitis, aka chronic fatigue syndrome (ME/CFS). He … Continue reading →

Posted in News | Tagged Dr Willy B Eriksen, EBV, Epstein Barr virus, inflammation, Tracy Duvall | Comments Off

The role of inflammation & over active immune system in depression

Posted on August 24, 2016 by wames

BBC news report, by James Gallagher, Rachael Buchanan & Andrew Luck-Baker, 24 August 2016: Depression: A revolution in treatment? The Inflamed Mind, BBC Radio 4 It’s not very often we get to talk about a revolution in understanding and treating depression … Continue reading →

Posted in News | Tagged anti-inflammatory drugs, BBC news, BBC Radio 4, depression, immune activation, inflammation, sirukomab, The inflamed mind | Comments Off

Is CFS/ME autoimmune & inflammatory?

Posted on July 22, 2016 by wames

VeryWell blog post, by Adrienne Dellwo [Reviewed by a board-certified physician], 8 July 2016: Is Chronic Fatigue Syndrome Autoimmune & Inflammatory? What We Know About It You still hear that chronic fatigue syndrome (ME/CFS) is a “mystery illness,” but the nature … Continue reading →

Posted in News | Tagged Adrienne Dellwo, autoimmune disorders, Epstein Barr virus, inflammation, inflammatory disorder, oxidative stress, Pall protocol, serotonin | Comments Off

Dr Neil Harrison videos for patients on the brain & inflammation in ME

Posted on July 12, 2016 by wames

Seven webinars of Dr Neil Harrison have been broadcast by the Dutch group ME/cvs Vereniging: 75, Mar 8, 2016: Me & ME: type of research, Models of inflammation, How does this relate to ME? 76, Mar 22 2016: ME & fatigue: How do you measure … Continue reading →

Posted in News | Tagged brain, chronic fatigue, diagnosis, Dr Neil Harrison, inflammation, ME/cvs Vereniging, videos | Comments Off

The Toll-Like Receptor Radical Cycle Pathway – the key to drug treatment for secondary chronic fatigue

Posted on April 20, 2016 by wames

Review abstract: In this review we discuss that peripheral and central activation of the Toll-like receptor 2/4 (TLR2/4) Radical Cycle may underpin the pathophysiology of immune-related chronic fatigue secondary to other medical diseases and conditions. The TLR Radical Cycle plays … Continue reading →

Posted in News | Tagged antioxidants, chronic fatigue, damage associated molecular patterns, DAMPs, inflammation, lipopolysaccharides, Oxidative and nitrosative stress, TLR2/4, Toll-like receptor 2/4 | Comments Off

Anti-citrullinated protein antibodies in CFS

Posted on January 5, 2016 by wames

The Vermont CFIDS Association reports on a recent pilot study and invites contributions to enable further research: While preliminary, the results from this University of Vermont study is the first evidence for the potential existence of autoantibodies in ME/CFS, indicative … Continue reading →

Posted in News | Tagged anti-citrullinated protein antibodies, autoantibodies, David Maughan, George Webb, immune system dysfunction, inflammation, Mercedes Rincon, Terence Naumann, Vermont CFIDS Association | Comments Off