Tag Archives: metabolites

Research: Kynurenine metabolites & ratios differ between CFS, FM, & healthy controls

Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls, by Nina Groven, Solveig Klæbo Reitan, Egil Andreas Fors, Ismail Cuneyt Guzey in Psychoneuroendocrinology 2021 May 27;131:105287 [doi: 10.1016/j.psyneuen.2021.105287]   Highlights: Quinolinic acid differs between CFS and … Continue reading

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Post-Exertional Malaise Is associated with hypermetabolism, hypoacetylation & purine metabolism deregulation in ME/CFS cases

Post-Exertional Malaise is associated with hypermetabolism, hypoacetylation and purine metabolism deregulation in ME/CFS cases, by Neil R McGregor, Christopher W Armstrong, Donald P Lewis and Paul R Gooley in Diagnostics 2019, 9(3), 70; [Published: 4 July 2019] https://doi.org/10.3390/diagnostics9030070 Research abstract: Post-exertional … Continue reading

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Comparison of differential metabolites in urine of the middle school students with CFS before & after exercise

Comparison of differential metabolites in urine of the middle school students with chronic fatigue syndrome before and after exercise [Article in Chinese], by Chi AP, Wang ZN, Shi B, Yang XF, Min RX, Song J in Zhongguo Ying Yong Sheng … Continue reading

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New CFS test is 84% accurate

Medical News Today blog post, by Ana Sandoiu, 11 July 2018: New chronic fatigue syndrome test is 84 percent accurate Myalgic encephalomyelitis/chronic fatigue syndrome does not currently have a diagnostic test. But this may soon change, as researchers have developed a … Continue reading

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Hyperactive brain in CFS – neurometabolites in anterior cingulate cortex

Research abstract: Neurometabolites in anterior cingulate cortex in chronic fatigue syndrome: a magnetic resonance spectroscopy study at 7 Tesla, by Chi Chen, [Master’s Thesis, Oxford University Sep 2017] Background: Chronic fatigue syndrome (CFS) is a disorder characterized by prolonged physical and mental fatigue that … Continue reading

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Possible clinical diagnostic tool for CFS based on the ratios of metabolites in blood plasma

Research abstract: Chronic fatigue syndrome (CFS) is a persistent and unexplained pathological state characterized by exertional and severely debilitating fatigue, with/without infectious or neuropsychiatric symptoms, lasting at least 6 consecutive months. Its pathogenesis remains incompletely understood. Here, we performed comprehensive … Continue reading

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The gut microbiome affects brain health

Research abstract The human gut microbiome impacts human brain health in numerous ways: (1) Structural bacterial components such as lipopolysaccharides provide low-grade tonic stimulation of the innate immune system. Excessive stimulation due to bacterial dysbiosis, small intestinal bacterial overgrowth, or … Continue reading

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