Tag Archives: molecular mimicry

A potential antigenic mimicry between viral & human proteins linking ME/CFS with autoimmunity: the case of HPV immunization

A potential antigenic mimicry between viral and human proteins linking Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with autoimmunity: the case of HPV immunization, by Jody Phelan, Anna D Grabowska, Nuno Sepulveda in Autoimmunity Reviews Vol 19, no. 4, April 2020,   1. Introduction … Continue reading

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ME/CFS in the era of the human microbiome

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in the era of the human microbiome: persistent pathogens drive chronic symptoms by interfering with host metabolism, gene expression and immunity, by Amy D Proal and Trevor Marshall in Front. Pediatr. 4 Dec 2018 The illness ME/CFS has … Continue reading

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Antibodies to adrenergic & muscarinic receptors in ME/CFS

Blog post, by Paolo Maccallini, 29 August 2017: Antibodies to adrenergic and muscarinic receptors in ME/CFS, During the Community Symposium on the molecular basis of ME/CFS two different groups of researchers reported on the increased level of antibodies to beta adrenergic and … Continue reading

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POTS, CFS and reactions to vaccines

Review article: Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system in which a change from the supine position to an upright position causes an abnormally large increase in heart rate or tachycardia (30 bpm within … Continue reading

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A proposal for treatment of harmful auto-antibodies in auto-immune disorders

Research abstract: The hypothesis proposed is that functional disorders, such as irritable bowel syndrome, chronic fatigue syndrome and anorexia nervosa are caused by auto-antibodies to neuronal proteins induced by molecular mimicry with microbial antigens. The age incidence of these conditions, … Continue reading

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Is CFS an autoimmune disorder with vasoactive neuropeptide dysfunction?

Abstract Chronic fatigue syndrome is a disorder characterised by prolonged fatigue and debility and is mostly associated with post-infection sequelae although ongoing infection is unproven. Immunological aberration is likely and this may prove to be associated with an expanding group … Continue reading

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