Tag Archives: NK cells

Loss of transient receptor potential Melastatin 3 ion channel function in natural killer cells from CFS/ME

Loss of Transient Receptor Potential Melastatin 3 ion channel function in natural killer cells from CFS/ME patients by Hélène Cabanas, Katsuhiko Muraki, Natalie Eaton, Cassandra Balinas, Donald Staines and Sonya Marshall-Gradisnik in Molecular Medicine 2018 24:44 [Published: 14 August 2018] Research abstract: … Continue reading

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Reduced glycolytic reserve in isolated natural killer cells from ME/CFS patients

Reduced glycolytic reserve in isolated natural killer cells from Myalgic encephalomyelitis/ chronic fatigue syndrome patients: A preliminary investigation, by Thao Nguyen, D Staines, S Johnston, S Marshall-Gradisnik in Asian Pac J Allergy Immunol. 2018 Jul 8. [Epub ahead of print] … Continue reading

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Association of T & NK cell phenotype with the diagnosis of ME/CFS

Research abstract: Association of T and NK cell phenotype with the diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), by Jose Luis Rivas, Teresa Palencia, Guerau Fernández, Milagros Garcia in Front. Immunol., 09 May 2018 Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is … Continue reading

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Rituximab impedes natural killer cell function in CFS/ME patients

Research abstract: Rituximab impedes natural killer cell function in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients: A pilot in vitro investigation by Natalie Eaton, Hélène Cabanas, Cassandra Balinas, Anne Klein, Donald Staines and Sonya Marshall-Gradisnik in BMC Pharmacology and Toxicology 2018 19:12 [Published: … Continue reading

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CFS and the immune system

Review summary: Chronic fatigue syndrome and the immune system: Where are we now?, by Fane Kojo Fosu Mensaha, Amolak Singh Bansal, Brian Ford, Geraldine Cambridge in Neurophysiologie Clinique/Clinical Neurophysiology [Available online 12 April 2017] Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterised by multiple … Continue reading

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Calcium mobilisation in natural killer cells & cell cytotoxicity in CFS/ME

Research abstract: Transient receptor potential melastatin subfamily 3 (TRPM3) ion channels play a role in calcium (Ca2+ ) cell signalling. Reduced TRPM3 has been identified in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) patients. However, the significance of TRPM3 and association with … Continue reading

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Dysregulation of protein kinase gene expression in NK Cells in CFS

Research abstract: BACKGROUND: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading

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CFS/ME cell discovery may hold key to treatment

Griffith University Media release, by Louise Durack, 9 June 2016: Chronic Fatigue Syndrome cell discovery may hold key to treatment: Chronic Fatigue Syndrome researchers have discovered a cell receptor which could be a key contributing factor to CFS, providing a … Continue reading

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Natural killer cell & SNP dysfunction in ME/CFS

Research abstract: Aim: The aim of this paper was to determine natural killer (NK) cytotoxic activity and if single nucleotide polymorphisms (SNPs) and genotypes in transient receptor potential (TRP) ion channels and acetylcholine receptors (AChRs) were present in isolated NK … Continue reading

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Low NK cell activity differs in ME/CFS & MS

Research abstract: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Multiple Sclerosis (MS) patients suffer from debilitating fatigue which is not alleviated by rest. In addition to the fatigue related symptoms suffered by CFS/ME and MS patients, dysfunction of the immune system … Continue reading

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