Tag Archives: Nuno Sepulveda

Research: Impact of misdiagnosis in studies of ME/CFS

Posted on 02/16/2023 by wames

Researchers need to increase study sizes and apply strict diagnostic criteria   Polish researchers report that the difficulties with diagnosing ME/CFS and ensuring all research participants have the same condition, can lead to inaccurate research results. Misdiagnosis can skew results … Continue reading →

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Research: Epstein-Barr Virus in ME/CFS

Posted on 08/01/2022 by wames

Revisiting IgG antibody reactivity to Epstein-Barr Virus in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome and its potential application to disease diagnosis Key research findings: Epstein-Barr virus (EBV) infection is commonly reported at the onset of ME/CFS, but could antibodies against EBV … Continue reading →

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Research review: Unknown aetiology: The case of ME/CFS and beyond

Posted on 03/02/2022 by wames

Current insights into complex Post-infection Fatigue Syndromes with unknown Aetiology: The case of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and beyond, by Francisco Westermeier, Eliana Mattos Lacerda,  Carmen Scheibenbogen and  Nuno Sepúlveda in Front. Med., 24 February 2022 [doi.org/10.3389/fmed.2022.862953]   Excerpts from … Continue reading →

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Research: Decreased NO production in endothelial cells… from ME/CFS patients

Posted on 02/18/2022 by wames

Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients, by R Bertinat, RVillalobos-Labra, L Hofmann, J Blauensteiner, N Sepúlveda, F Westermeir in Vascular Pharmacology 2022, 106953 [doi.org/10.1016/j.vph.2022.106953]   Highlights ME/CFS-plasma reduced the ability of ECs to produce NO. … Continue reading →

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Research: The SARS-CoV-2 receptor ACE2 in ME/CFS

Posted on 09/08/2021 by wames

The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in  Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: a meta-analysis of public DNA methylation and gene expression data, by João Malato, Franziska Sotzny, Sandra Bauer, Helma Freitag, André Fonseca, Anna D Grabowska, Luís Graça, Clara Cordeiro, … Continue reading →

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Research: Herpesviruses serology distinguishes different subgroups of ME/CFS patients

Posted on 07/30/2021 by wames

Herpesviruses serology distinguishes different subgroups of patients from the United Kingdom Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Biobank, by Tiago Dias Domingues, Anna D Grabowska, Ji-Sook Lee, Jose Ameijeiras-Alonso, Francisco Westermeier, Carmen Scheibenbogen, Jacqueline M Cliff, Luis Nacul, Eliana M Lacerda, Helena … Continue reading →

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Review of the quality control checks performed by current genome-wide & targeted-genome association studies on ME/CFS

Posted on 05/28/2020 by wames

Review of the quality control checks performed by current genome-wide and targeted-genome association studies on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Nuno Sepulveda, Anna D Grabowska, Eliana M Lacerda, Luis C Nacul in Frontiers in Pediatrics. May 7, 2020 [doi: 10.3389/fped.2020.00293 … Continue reading →

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Systematic review of the epidemiological burden of ME/CFS across Europe: current evidence & EUROMENE research recommendations for epidemiology

Posted on 05/27/2020 by wames

Systematic review of the epidemiological burden of ME/CFS across Europe: current evidence and EUROMENE research recommendations for epidemiology, by Fernando Estévez-López, Kathleen Mudie, Xia Wang-Steverding, Inger Johanne Bakken, Andrejs Ivanovs, Jesús Castro-Marrero, Luis Nacul, Jose Alegre, Paweł Zalewski, Joanna Słomko, … Continue reading →

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A potential antigenic mimicry between viral & human proteins linking ME/CFS with autoimmunity: the case of HPV immunization

Posted on 05/02/2020 by wames

A potential antigenic mimicry between viral and human proteins linking Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with autoimmunity: the case of HPV immunization, by Jody Phelan, Anna D Grabowska, Nuno Sepulveda in Autoimmunity Reviews Vol 19, no. 4, April 2020,   1. Introduction … Continue reading →

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ME/CFS as a hyper-regulated immune system driven by an interplay between regulatory T cells & chronic human herpesvirus infections

Posted on 11/22/2019 by wames

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome as a hyper-regulated immune system driven by an interplay between regulatory T cells and chronic human herpesvirus infections, by Nuno Sepúlveda,  Jorge Carneiro,  Eliana M Lacerda and  Luis C Nacul in Front. Immunol. 21 Nov 2019 … Continue reading →

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