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Research: Fitbit trackers & PROMs help monitor ME/CFS activity
Activity monitoring and patient-reported outcome measures in ME/CFS patients A small Norwegian study from the team led by Prof Olav Mella and Dr Oystein Fluge trialled wearable activity trackers and questionnaires to monitor heart rate and activity to aid pacing … Continue reading
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Tagged activity trackers, DePaul Symptom Questionnaire, Dr Oystein Fluge, DSQ-SF, Fitbit, heart rate monitoring, Ingrid G Rekeland, Kari Sorland, Karl J Tronstad, Kine Alme, Kristin Risa, Olav Dahl, Ove Bruland, Prof Olav Mella, PROMS, SF-36, Short form 36, wearable sensor
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Research: Genetic association study in ME/CFS
Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci, by Riad Hajdarevic, Asgeir Lande, Jesper Mehlsen, Anne Rydland, Daisy D Sosa, Elin B Strand, Olav Mella, Flemming Pociot, Øystein Fluge, Benedict A Lie, Marte K … Continue reading
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Tagged Anne Rydland, Asgeir Lande, Benedict A Lie, Daisy D Sosa, Elin B Strand, Flemming Pociot, genome-wide association study, GWAS, immunochip, Jesper Mehlsen, Marte K Viken, Øystein Fluge, Prof Olav Mella, Riad Hajdarevic
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Genetic research: Fine mapping of the major histocompatibility complex (MHC) in ME/CFS
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci, by Riad Hajdarevic, Asgeir Lande, Ingrid Rekeland, Anne Rydland, Elin B Strand, Daisy D Sosa, … Continue reading
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Tagged Anne Rydland, Asgeir Lande, Benedicte A Lie, Daisy D Sosa, Elin B Strand, gene expression, HLA fine-mapping, Human leukocyte antigen, Ingrid Rekeland, Lisa E Creary, Marte K Viken, Ola D Saugstad, Øystein Fluge, Prof Olav Mella, Riad Hajdarevic, Torstein Egeland
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Research: Pathomechanisms & possible interventions in ME/CFS
Pathomechanisms and possible interventions in myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS), by Øystein Fluge, Karl J. Tronstad, and Olav Mella in J Clin Invest. 2021;131(14):e150377 [doi.org/10.1172/JCI150377] July 15, 2021 Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease with … Continue reading
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Tagged circulatory impairment, Dr Oystein Fluge, immune dysregulation, pathomechanism, Prof Karl Johan Tronstad, Prof Olav Mella
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Intravenous cyclophosphamide in ME/CFS. An open-label phase II study
Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study by Ingrid G Rekeland, Alexander Fosså, Asgeir Lande, Irini Ktoridou-Valen, Kari Sørland, Mari Holsen, Karl J Tronstad, Kristin Risa, Kine Alme, Marte K Viken, Benedicte A Lie, Olav … Continue reading
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Tagged Alexander Fosså, Asgeir Lande, Benedicte A Lie, cancer, chemotherapy, CycloME study, Cyclophosphamide, Ingrid G Rekeland, Irini Ktoridou-Valen, Kari Sorland, Karl J Tronstad, Kine Alme, Kristin Risa, Mari Holsen, Marte K Viken, Olav Dahl, Øystein Fluge, Prof Olav Mella
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Human Leukocyte Antigen alleles associated with ME/CFS
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), by Asgeir Lande, Øystein Fluge, Elin B Strand, Siri T Flåm, Daysi D Sosa, Olav Mella, Torstein Egeland, Ola D Saugsta, Benedicte A Lie, Marte K Viken in Scientific … Continue reading
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Tagged autoimmune disorders, Benedicte A Lie, Daysi D Sosa, Dr Oystein Fluge, Elin B Strand, genes, genotypes, HLA genes, human leukocyte antigen molecules, Marte K Viken, Ola D Saugsta, Prof Olav Mella, Siri T Flåm, Torstein Egeland
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B-Lymphocyte depletion in patients with ME/CFS: the final rituximab trial results
B-lymphocyte depletion in patients With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: a randomized, double-blind, placebo-controlled trial by Oystein Fluge, Ingrid G. Rekeland, Katarina Lien, Hanne Thurmer, Petter C. Borchgrevink, Christoph Schafer, Kari Sorland, Jorg Assmus, Irini Ktoridou-Valen, Ingrid Herder, Merethe E. … Continue reading
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Tagged B-lymphocyte depletion, Dr Oystein Fluge, Dr Peter Rowe, Prof Olav Mella, rituxan, rituximab
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Immunosignature analysis of ME/CFS – promising diagnostic biomarker
Immunosignature Analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Oliver P Günther, Jennifer L Gardy, Phillip Stafford, Øystein Fluge, Olav Mella, Patrick Tang, Ruth R Miller, Shoshana M Parker, Stephen A Johnston, David M Patrick in Molecular Neurobiology (2018) pp 1-9 [Published online: … Continue reading
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Tagged biomarker, diagnostic marker, Dr David Patrick, Dr Oystein Fluge, immune dysfunction, immunosignature, Jennifer L Gardy, Oliver P Günther, Patrick Tang, Phillip Stafford, Prof Olav Mella, Ruth R Miller, Shoshana M Parker, Stephen A Johnston
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Norwegian rituximab trial reports negative results
The Norwegian Rituximab trial reports negative results ahead of the publication of the full results. Attempts are now under way to determine the best way forward in understanding what has been learned and how to find out which patients may still benefit from … Continue reading
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Tagged B-cell, Cort Johnson, Cyclophosphamide, Dr Oystein Fluge, Prof Olav Mella, rituximab, Simmaron Research
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