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Research: Symptom-based clusters (sub-groups) in ME/CFS
Finding sub-groups in ME/CFS Prof Leonard Jason worked with Dutch researchers to identify sub-groups of ME/CFS patients by symptom clusters. They used Leonard’s DePaul Symptom Questionnaire and data analysis software SOM. 45 subgroups were identified, some small. The researchers … Continue reading
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Tagged Anouk W Vaes, Jeannet M Delbressine, Maarten Van Herck, Martijn A Spruit, Prof Leonard Jason, Qichen Deng, Self-Organizing Maps, SOM software, sub-groups, symptom clusters
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Integration of DNA methylation & health scores identifies subtypes in ME/CFS
Research abstract: Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome, by Wilfred C de Vega, Lauren Erdman, Suzanne D Vernon, Anna Goldenberg & Patrick O McGowan in Epigenomics. 2018 Apr 25. doi: 10.2217/epi-2017-0150. [Epub … Continue reading
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Tagged Anna Goldenberg, clinical subtyping, DePaul Symptom Questionnaire, DNA methylation, Dr Patrick O McGowan, Dr Suzanne Vernon, epigenetics, Lauren Erdman, RAND-36 Short Form Survey, sub-groups, Wilfred C de Vega
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Subtyping patients with ME & CFS by course of illness
Research Abstract: Subtyping Patients with Myalgic Encephalomyelitis (ME) and Chronic Fatigue Syndrome (CFS) By Course of Illness, by Jamie Stoothoff, Kristen Gleason, Stephanie McManimen, Taylor Thorpe and Leonard A. Jason in Symbiosis: Journal of Biosensors, Biomarkers and Diagnostics [Published: June 26, … Continue reading
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Tagged illness trajectory, Jamie Stoothoff, Kristen Gleason, Prof Leonard Jason, Stephanie L McManimen, sub-groups, Taylor Thorpe
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Elevated energy production by non-mitochondrial sources in CFS sub-group
Research abstract: Chronic Fatigue Syndrome (CFS) is a debilitating disease characterized by physical and mental exhaustion. The underlying pathogenesis is unknown, but impairments in certain mitochondrial functions have been found in some CFS patients. To thoroughly reveal mitochondrial deficiencies in … Continue reading
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Tagged ATP, Chung-Han Hsieh, Dana March, glycolysis, mitochondrial dysfunction, Nick Lawson, sub-groups, Xinnan Wang
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