PACE trial finds that CBT and GET are a ‘moderately effective’ treatment for 60% of people with CFS/ME, whose primary symptom is fatigue.’

The PACE trial recruited 640 patients who met the Oxford criteria for CFS from 6 UK CFS clinics. The aim was to assess after a year the effectiveness of SMC (Specialist Medical Care), APT (Adaptive Pacing Therapy), GET (Graded Exercise Therapy) and CBT (Cognitive behavioural Therapy). They concluded that CBT and GET can safely be added to SMC to moderately improve outcomes for chronic fatigue syndrome, but APT is not an effective addition and their findings were published in the Lancet.