Category Archives: News

Cytokine flucutations reflect fluctutations in fatigue severity

Research Abstract Background: Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by persistent fatigue that is not alleviated by rest. The lack of a clearly identified underlying mechanism has hindered the development of effective treatments. Studies have demonstrated elevated … Continue reading

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Headaches (idiopathic intracranial hypertension) & CFS

Research Abstract Introduction: Headache is common in chronic fatigue syndrome, a condition of unknown cause in which there are no clinical signs. Fatigue is common in idiopathic intracranial hypertension, a headache condition of unknown cause in which the only clinical … Continue reading

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Patterns of Abnormal Visual Attention in ME

 Research Abstract Purpose: To experimentally assess visual attention difficulties commonly reported by those with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Methods:  Twenty-nine ME/CFS patients and 29 controls took part in the study. Performance was assessed using the Useful Field of View … Continue reading

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Physiotherapist warns about graded exercise therapy (GET) in ME/CFS

Physio Michelle Bull has a special interest in exercise for people with chronic fatigue – because her son has the condition I read the article about graded exercise therapy (GET) (Frontline, 20 March) with great interest as a physiotherapist and … Continue reading

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Sleep disorders in CFS

Research Abstract Objectives:  Despite sleep disturbances being a central complaint in patients with chronic fatigue syndrome (CFS), evidence of objective sleep abnormalities from over 30 studies is inconsistent. The present study aimed to identify whether sleep-specific phenotypes exist in CFS … Continue reading

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Evidence from research into childhood CFS/ME is lacking

Review Abstract Purpose  A range of interventions have been used for the management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in children and adolescents. Currently, debate exists as to the effectiveness of these different management strategies. The objective of this review … Continue reading

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Diagnosis difficulties for black and minority ethnic people in UK

Research Abstract Aim   This study aims to explore the possible reasons for the lower levels of diagnosis of chronic fatigue syndrome/myalgic encephalitis (CFS/ME) in the black and minority ethnic (BME) population, and the implications for management. BACKGROUND:    Population studies suggest … Continue reading

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A strategy for defining and distinguishing ME & CFS

 Abstract The symptom spectrum of Myalgic Encephalomyelitis (ME) was first detailed in 1959 and later operationalised into a diagnostic protocol (Melvin Ramsey). In 1988 the Holmes case definition coined the term chronic fatigue syndrome (CFS). Fukuda’s Centers for Disease Control … Continue reading

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Definitions of CFS/ME used in prevalence research

Abstract Purpose Prevalence estimates have been based on several case definitions of chronic fatigue syndrome (CFS). The purpose of this work is to provide a rigorous overview of their application in prevalence research. Methods A systematic review of primary studies … Continue reading

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Increased 5-HT autoimmune activity in ME/CFS

Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is accompanied by activation of immuno-inflammatory pathways, increased bacterial translocation and autoimmune responses to serotonin (5-HT). Inflammation is known to damage 5-HT neurons while bacterial translocation may drive autoimmune responses. This study has … Continue reading

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