Category Archives: News
Cytokine flucutations reflect fluctutations in fatigue severity
Research Abstract Background: Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by persistent fatigue that is not alleviated by rest. The lack of a clearly identified underlying mechanism has hindered the development of effective treatments. Studies have demonstrated elevated … Continue reading
Headaches (idiopathic intracranial hypertension) & CFS
Research Abstract Introduction: Headache is common in chronic fatigue syndrome, a condition of unknown cause in which there are no clinical signs. Fatigue is common in idiopathic intracranial hypertension, a headache condition of unknown cause in which the only clinical … Continue reading
Patterns of Abnormal Visual Attention in ME
Research Abstract Purpose: To experimentally assess visual attention difficulties commonly reported by those with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Methods: Twenty-nine ME/CFS patients and 29 controls took part in the study. Performance was assessed using the Useful Field of View … Continue reading
Physiotherapist warns about graded exercise therapy (GET) in ME/CFS
Physio Michelle Bull has a special interest in exercise for people with chronic fatigue – because her son has the condition I read the article about graded exercise therapy (GET) (Frontline, 20 March) with great interest as a physiotherapist and … Continue reading
Sleep disorders in CFS
Research Abstract Objectives: Despite sleep disturbances being a central complaint in patients with chronic fatigue syndrome (CFS), evidence of objective sleep abnormalities from over 30 studies is inconsistent. The present study aimed to identify whether sleep-specific phenotypes exist in CFS … Continue reading
Evidence from research into childhood CFS/ME is lacking
Review Abstract Purpose A range of interventions have been used for the management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in children and adolescents. Currently, debate exists as to the effectiveness of these different management strategies. The objective of this review … Continue reading
Diagnosis difficulties for black and minority ethnic people in UK
Research Abstract Aim This study aims to explore the possible reasons for the lower levels of diagnosis of chronic fatigue syndrome/myalgic encephalitis (CFS/ME) in the black and minority ethnic (BME) population, and the implications for management. BACKGROUND: Population studies suggest … Continue reading
A strategy for defining and distinguishing ME & CFS
Abstract The symptom spectrum of Myalgic Encephalomyelitis (ME) was first detailed in 1959 and later operationalised into a diagnostic protocol (Melvin Ramsey). In 1988 the Holmes case definition coined the term chronic fatigue syndrome (CFS). Fukuda’s Centers for Disease Control … Continue reading
Definitions of CFS/ME used in prevalence research
Abstract Purpose Prevalence estimates have been based on several case definitions of chronic fatigue syndrome (CFS). The purpose of this work is to provide a rigorous overview of their application in prevalence research. Methods A systematic review of primary studies … Continue reading
Increased 5-HT autoimmune activity in ME/CFS
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is accompanied by activation of immuno-inflammatory pathways, increased bacterial translocation and autoimmune responses to serotonin (5-HT). Inflammation is known to damage 5-HT neurons while bacterial translocation may drive autoimmune responses. This study has … Continue reading