An open access e-book published in Feb 2012 presents 5 articles. A common theme in them all is CFS as a multisystem disease with the possibility of more than one cause and influenced by a variety of interacting factors. Further, they acknowledge the reality of CFS for persons with this disease and the importance of finding causes, treatments and ultimately a cure. As advanced biomedical research techniques are increasingly applied to the study of CFS, it is surely only a matter of time before biomarkers are identified, aetiologies understood, and remedies devised.

• Chapter 1 Chronic Fatigue Syndrome and Viral Infections – Frédéric Morinet and Emmanuelle Corruble
• Chapter 2 Gene Expression in Chronic Fatigue Syndrome Ekua W. Brenu et al
• Chapter 3 Integrated Analysis of Gene Expression and Genotype Variation Data for Chronic Fatigue Syndrome – Jungsoo Gim and Taesung Park
• Chapter 4 Corticosteroid-Binding Globulin Gene Mutations and Chronic Fatigue/Pain Syndromes: An Overview of Current Evidence – C. S. Marathe and D. J. Torpy
• Chapter 5 Small Heart as a Constitutive Factor Predisposing to Chronic Fatigue Syndrome – Kunihisa Miwa

 An International Perspective on the Future of Research in Chronic Fatigue Syndrome