Tag Archives: 5-HT
Targeting serotonin and insulin-like growth factor in CFS
Thesis outline: Given the controversies and uncertainties surrounding these potentially important mediators in CFS, we decided to investigate the role of tryptophan, 5-HT and IGF-1 in CFS in this thesis. Our studies aim to obtain a deeper insight into the … Continue reading
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Tagged 5-HT, Acclydine, Gerard Kong Han The, Granisetron, IGF-1, Ondansetron, serotonin
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Increased 5-HT autoimmune activity in ME/CFS
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is accompanied by activation of immuno-inflammatory pathways, increased bacterial translocation and autoimmune responses to serotonin (5-HT). Inflammation is known to damage 5-HT neurons while bacterial translocation may drive autoimmune responses. This study has … Continue reading
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Tagged 5-HT, autoimmune, cytokines, inflammation
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