Tag Archives: case definitions

A comparison of case definitions for ME & CFS

Research abstract: A Comparison of Case Definitions for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome, by Madison Sunnquist, Leonard A Jason, P Nehrke, Ellken M Goudsmit in Chronic Dis Manag. 2017;2(2). pii: 1013. Epub 2017 May 21 Many professionals have described the … Continue reading

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Scientific progress stumbles without a valid case definition

OUP blog post, by Leonard A. Jason, August 20th 2017: Scientific progress stumbles without a valid case definition Current estimates from the Centers for Disease Control and Prevention (CDC) of the number of people in the United States with chronic … Continue reading

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Is SEID comparable to research case definitions of CFS?

Two groups of American researchers debate the appropriateness of using case definitions for research purposes. Article abstract: Mistaken conclusions about systemic exercise intolerance disease being comparable to research case definitions of CFS: a rebuttal to Chu et al., by Leonard A. Jason, Madison Sunnquist, Kristen … Continue reading

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Video lecture on clinical case definitions by Prof Jason

Youtube video published 17 March 2017: Leonard Jason’s Presentation on Case Definitions to European Network The issue of research and clinical case definitions were discussed in this 30 min March 2-017 talk, and then the European scientists asked questions for the remaining 30 … Continue reading

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Standard research criteria would aid ME/CFS research

Research abstract: Background: The Institute of Medicine (IOM) recently developed clinical criteria for what had been known as chronic fatigue syndrome. Given the broad nature of the clinical IOM criteria, there is a need for a research definition that would … Continue reading

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Differing case definitions point to the need for an accurate diagnosis of ME/CFS

Research article: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterised by unexplained and persistent or recurrent incapacitating fatigue accompanied by a variety of symptoms and substantial reductions in previous levels of occupational, educational, social and/or personal activity [1,2]. Given the absence … Continue reading

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Developing case definitions for ME and CFS using practical experience and consensus

Research abstract: Background: There has been considerable controversy regarding how to name and define the illnesses known as myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). The Institute of Medicine (IOM) report has proposed new clinical criteria and a new name for this … Continue reading

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Variability in symptoms complicates usefulness of case definitions

Research abstract: Background: Ambiguities in case definitions have created difficulties in replicating findings and estimating the prevalence rates for chronic fatigue syndrome (CFS) and Myalgic Encephalomyelitis (ME). Purpose: The current study examined differences in occurrence rates for CFS and ME … Continue reading

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Comparison of consensus & empirical ME/CFS definitions & criteria

Research abstract: Background:  Since the publication of the CFS case definition [Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue  syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994;121:953-959], there … Continue reading

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