Tag Archives: Dr Leonard Jason
Associations between autonomic & orthostatic self-report and physician ratings of Orthostatic Intolerance in youth
Associations between autonomic and orthostatic self-report and physician ratings of Orthostatic Intolerance in youth, by Katlin R Schultz, Ben Z Katz, Neil R Bockian, Leonard A Jason in Clinical Therapeutics 2019 Research abstract: Purpose: There is no known biological marker or physical assessment … Continue reading
Key issues for understanding ME, biological markers & diagnostic criteria
Review abstract: Myalgic Encephalomyelitis (ME) continues to cause significant morbidity worldwide with an estimated one million cases in the United States. Hurdles to establishing consensus to achieve accurate evaluation of patients with ME continue, fuelled by poor agreement about case definitions, … Continue reading
Dr Leonard Jason’s reflections on SEID
Article abstract: The Institute of Medicine (IOM) in the US has recently proposed that the term Systemic Exertion Intolerance Disease (SEID) replace Chronic Fatigue Syndrome (CFS). In addition, the IOM proposed a new case definition for SEID, which includes substantial … Continue reading
Parent carers’ experiences with severe ME
Research abstract: Experiences of parents who care for sons or daughters with severe myalgic encephalomyelitis are rarely discussed within the literature. Narratives of parent-carers in Lost Voices from a Hidden Illness were analyzed using interpretative phenomenological analysis. This study aimed … Continue reading
Variability in symptoms complicates usefulness of case definitions
Research abstract: Background: Ambiguities in case definitions have created difficulties in replicating findings and estimating the prevalence rates for chronic fatigue syndrome (CFS) and Myalgic Encephalomyelitis (ME). Purpose: The current study examined differences in occurrence rates for CFS and ME … Continue reading
Problems in defining Post exertional malaise
Research abstract: Post-exertional malaise (PEM) is a cardinal symptom of the illnesses referred to as Myalgic Encephalomyelitis (ME), Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS), and chronic fatigue syndrome (CFS). PEM is reported to occur in many of these patients, and with … Continue reading
Useful symptom questionnaire to aid ME diagnosis
Research abstract Background: The DePaul Symptom Questionnaire (DSQ) was developed to provide a structured approach for collecting standardized symptomatology and health history information to allow researchers and clinicians to determine whether a patient meets the diagnostic criteria for myalgic encephalomyelitis/chronic … Continue reading



