Tag Archives: Dr Sonja Marshall Gradisnik
A systematic review of mitochondrial abnormalities in ME/CFS/SEID
A systematic review of mitochondrial abnormalities in myalgic encephalomyelitis/chronic fatigue syndrome/systemic exertion intolerance disease, by Sean Holden, Rebekah Maksoud, Natalie Eaton-Fitch, Hélène Cabanas, Donald Staines & Sonya Marshall-Gradisnik in Journal of Translational Medicine vol 18, no: 290 (2020)[doi.org/10.1186/s12967-020-02452-3] Review … Continue reading
Australian researchers discover abnormalities in immune cell receptors in ME/CFS
Huffington Post Australia, by Luke Cooper, 22 Feb 2017: Queensland Scientists Make Chronic Fatigue Syndrome Research Breakthrough The condition has been linked to abnormal immune system cells. Queensland scientists have linked Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis … Continue reading
Dysregulation of protein kinase gene expression in NK Cells in CFS
Research abstract: BACKGROUND: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading
Systematic review of drug therapies for CFS/ME finds no drugs universally effective
Review abstract: Purpose: The pathogenesis of chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is complex and remains poorly understood. Evidence regarding the use of drug therapies in CFS/ME is currently limited and conflicting. The aim of this systematic review was to examine the existing evidence on … Continue reading
Natural killer cell & SNP dysfunction in ME/CFS
Research abstract: Aim: The aim of this paper was to determine natural killer (NK) cytotoxic activity and if single nucleotide polymorphisms (SNPs) and genotypes in transient receptor potential (TRP) ion channels and acetylcholine receptors (AChRs) were present in isolated NK … Continue reading
Promising Australian research could lead to diagnostic test
Griffith University press release: Screening test for Chronic Fatigue Syndrome on its way Ground-breaking research at Griffith University into Chronic Fatigue Syndrome (CFS) is leading the way for the development of a new screening tool for the condition. The research … Continue reading
B cells in the immune systems of people with CFS
Research abstract Limited immunological changes have been previously reported in B cell phenotype in Chronic Fatigue Syndrome (CFS) patients, so there is no clear established role of B cells in the pathophysiology of CFS patients. The aim of this study … Continue reading
