Tag Archives: epigenetics

Research: DNA changes during a relapse and recovery cycle in ME/CFS

Dynamic epigenetic changes during a relapse and recovery cycle in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome   Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work. Unlike genetic changes, epigenetic … Continue reading

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DNA Methylation & BDNF expression account for symptoms & widespread hyperalgesia in patients with CFS & FM

DNA Methylation and BDNF Expression account for symptoms and widespread hyperalgesia in patients with Chronic Fatigue Syndrome and Fibromyalgia, by Andrea Polli, Manosij Ghosh, Jelena Bakusic, Kelly Ickmans, Dora Monteyne, Brigitte Velkeniers, Bram Bekaert, Lode Godderis, Jo Nijs in Arthritis … Continue reading

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Epigenetic components of ME/CFS uncover potential Transposable Element activation

Epigenetic components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover potential Transposable Element Activation, by  Eloy Almenar-Pérez, Tamara Ovejero PhD, Teresa Sánchez-Fito MSc, José A Espejo BSc, Lubov Nathanson PhD, Elisa Oltra PhD, in Clinical Therapeutics [Published online 23 March 2019] https://doi.org/10.1016/j.clinthera.2019.02.012 … Continue reading

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Genome-epigenome interactions associated with ME/CFS

Genome-epigenome interactions associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Santiago Herrera, Wilfred C de Vega, David Ashbrook, Suzanne D Vernon and Patrick O McGowan in Epigenetics 2018 [Published online: 5 Dec 2018]   Research abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) … Continue reading

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System reset? Study suggests Pro-Inflammatory / Autoimmune reset in ME/CFS

Simmaron Research blog post, by Cort Johnson, 4 August 2018: System Reset? Study Suggests Pro-Inflammatory / Autoimmune Reset Occurred in Chronic Fatigue Syndrome (ME/CFS) Epigenetics research holds the fascinating possibility of figuring out what shifted at the very beginning of chronic … Continue reading

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Identification of ME/CFS-associated DNA methylation patterns

Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns, by Malav S. Trivedi, Elisa Oltra, Leonor Sarria, Natasha Rose, Vladimir Beljanski, Mary Ann Fletcher, Nancy  G. Klimas, Lubov Nathanson in PLoS One Vol 13, #7, p e0201066 [Published: July 23, 2018] Abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue … Continue reading

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Integration of DNA methylation & health scores identifies subtypes in ME/CFS

Research abstract: Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome, by Wilfred C de Vega, Lauren Erdman, Suzanne D Vernon, Anna Goldenberg & Patrick O McGowan in Epigenomics. 2018 Apr 25. doi: 10.2217/epi-2017-0150. [Epub … Continue reading

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Epigenetics study highlights metabolic problems in ME/CFS

Health rising blog post, by Cort Johnson, 30 July 2017: Epigenetics Study Highlights Metabolic Problems in Chronic Fatigue Syndrome (ME/CFS) There was a time that the HPA axis was “it” in chronic fatigue syndrome. More studies have been done on … Continue reading

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Epigenetic modifications & glucocorticoid sensitivity in ME/CFS

Research abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating idiopathic disease characterized by unexplained fatigue that fails to resolve with sufficient rest. Diagnosis is based on a list of symptoms and exclusion of other fatigue-related health conditions. Despite … Continue reading

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Changes to genes found in IBS

Research abstract: Background: Irritable bowel syndrome (IBS) is a stress-sensitive disorder. Environmental factors including stress can trigger epigenetic changes, which have not been well-studied in IBS. We performed a pilot study investigating genome-wide DNA methylation of IBS patients and healthy … Continue reading

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