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Prof Alan Light videos on fatigue and gene expression in ME/CFS
Professor Alan Light, from Utah University, talks about his involvement with ME in videos posted on the Dutch Youtube site ME/cvs Vereniging. no. 58 Fatigue – the differences between generalised fatigue and the fatigue of ME/CFS no. 59 Genes & gene expression & … Continue reading
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Tagged chronic fatigue, gene expression, genes, ME/cvs Vereniging, Prof Alan Light
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Rituximab interviews
Two Norwegian scientists, Øystein Fluge and Olav Mella, who have been researching the effects of an anti-lymphoma drug called Rituximab on people with ME/CFS, talked about their work on the BBC Radio Cambridgeshire programme ‘Naked Scientists’ on Sunday, 22 March. … Continue reading
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Tagged autoimmune disorders, BBC radio, blood vessels, cardiopulmonary tests, Cyclophosphamide, Dr Olav Mella, Dr Oystein Fluge, endothelial dysfunction, exercise tests, gastrointestinal disorder, gene expression, immunomodulatory drug, rituximab, Teresa Grøtan
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Video presentation of Alan Light’s gene expression research
“Using Gene Expression to Objectively Subset & Diagnose FM, CFS and Depression” Published on Dec 18, 2014 Alan Light, PhD gave this presentation during OFFER’s 2014 Healthcare Provider Conference. In this study, they looked at 46 genes [using the leukocytes] … Continue reading
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Tagged Alan R Light, diagnosis, gene expression, subgroups
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Fatigue in MS and ME: similarities and differences
Cort Johnson in his blog Health rising asks if the fatigue found in MS and ME is similar or different: Simply looking at the symptoms indicated that MS is primarily a fatiguing disorder, and that MS patients may, in fact, … Continue reading
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Tagged Alan R Light, Cort Johnson, fatigue, gene expression, PEM, Post-exertional malaise, Post-Exertional Relapse Syndrome
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SNPs in CFS/ME genes could lead to diagnostic test for CFS/ME subtypes
Research abstract Aims We have reported gene expression changes in patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and the fact that such gene expression data can be used to identify subtypes of CFS/ME with distinct clinical phenotypes. Due to the … Continue reading
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Tagged biomarkers, diagnostic test, DNA, gene expression, single-nucleotide polymorphism, SNP allele, SNPs
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The importance of understanding how our genes change
Extract from article by Cort Johnson: Epigenetics refers to the changes in sites in our DNA that are susceptible to change over time which can modify the expression of our genes. Our genetic heritage, it turns out, only sets the … Continue reading
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Tagged Cort Johnson, DNA, epigenetics, gene expression, gene modification, Patrick O McGowan
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Videos of expert lectures from Stanford ME/CFS Symposium 2014
Advances in Clinical Care and Translational Research: a Continuing Medical Education Conference Presented by the Department of Medicine and Division of Infectious Diseases and Geographic Medicine at Stanford University School of Medicine and Stanford Hospital & Clinics. March 19, 2014 … Continue reading
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Tagged Amit Kaushal, cardiovascular aging, Cortical pathology, David Tuller, Elizabeth R. Unger, epidemiology, Erin Allday, gene expression, Gut microbes, Jarred Younger, Jose G Montoya, Marcie Zinn, Mark Zinn, media protrayal, Mehdi Skhiri, Michael Zeineh, MRI, Natalie Boulton, Prof Anthony Komaroff, Prof Ian Lipkin, Stanford ME/CFS Initiative, videos
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Altered immune response to exercise in CFS/ME
Abstract An increasing number of studies have examined how the immune system of patients with Chronic Fatigue Syndrome (CFS), or myalgic encephalomyelitis, responds to exercise. The objective of the present study was to systematically review the scientific literature addressing … Continue reading
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Tagged exercise, gene expression, immune system, J Nijs, oxidative stress
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Fatigue in cancer and CFS
Abstract BACKGROUND Androgen deprivation therapy (ADT) often worsens fatigue in patients with prostate cancer, producing symptoms similar to chronic fatigue syndrome (CFS). Comparing expression (mRNA) of many fatigue-related genes in patients with ADT-treated prostate cancer versus with CFS versus healthy … Continue reading
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Tagged ADT, Androgen deprivation therapy, cancer, DBI, fatigue, GABA-A receptor modulator, gene expression
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Post-exertion malaise in CFS: symptoms & gene expression
Research abstract BACKGROUND A primary complaint of chronic fatigue syndrome (CFS) patients is post-exertion malaise, which is a worsening of symptoms following activities such as exercise. PURPOSE To examine the link between gene expression for metabolite, adrenergic, immune, and glucocorticoid … Continue reading
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Tagged Alan R Light, gene expression, glucocorticoid sensitivity, Jacob D Meyer, PEM, Post-exertional malaise
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