Tag Archives: HPA axis functioning
Hypothesis: Cerebrospinal fluid pressure increase in CFS & FM
The role of increased cerebrospinal fluid pressure in CFS and FM Belgian researchers reviewed research literature to find characteristics signs that are shared with empty sella syndrome and suggest that moderate or intermittent increases in cerebrospinal fluid pressure are … Continue reading
Research review: COVID-19 & CFS: an endocrine perspective
COVID-19 and Chronic Fatigue Syndrome: An endocrine perspective, by Rashika Bansal, Sriram Gubbi, Christian A Koch in Journal of Clinical & Translational Endocrinology 3 Dec 2021 [doi.org/10.1016/j.jcte.2021.100284] Research abstract: Patients recovering from COVID-19 may have persistent debilitating symptoms requiring … Continue reading
Neuroendocrine disorder in CFS
Research abstract: Neuroendocrine disorder in chronic fatigue syndrome, by Slavica TOMIC, Snezana BRKIC, Dajana LENDAK, Daniela MARIC, Milica MEDIC STOJANOSKA, Aleksandra NOVAKOV MIKIC in Turkish Journal of Medical Sciences (2017) 47: sag-1601-110 [Published Online: 17 Dec 2016] Background/aim: Neuroendocrine disorders are … Continue reading
Epigenetic modifications & glucocorticoid sensitivity in ME/CFS
Research abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating idiopathic disease characterized by unexplained fatigue that fails to resolve with sufficient rest. Diagnosis is based on a list of symptoms and exclusion of other fatigue-related health conditions. Despite … Continue reading
Altered neuroendocrine control in adolescent CFS
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is a common and disabling disorder, and a major threat against adolescent health. The pathophysiology is unknown, but alteration of neuroendocrine control systems might be a central element, resulting in attenuation of the … Continue reading
Altered neuroendocrine control & association to clinical symptoms in adolescent CFS
Research abstract: Background: Chronic fatigue syndrome (CFS) is a common and disabling disorder, and a major threat against adolescent health. The pathophysiology is unknown, but alteration of neuroendocrine control systems might be a central element, resulting in attenuation of the … Continue reading
Perfectionism & stress in CFS could be due to HPA dysregulation
Article Background: There is increasing evidence that Chronic Fatigue Syndrome (CFS) may reflect a dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis after a prolonged period of hyperactivity due to chronic stress/overload. We and others have hypothesized that chronic stress and subsequent … Continue reading
COMT gene dysfunction linked to susceptibility to infection in CFS
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is considered as a neuroimmunological disease but the etiology and pathophysiology is poorly understood. Patients suffer from sustained exhaustion, cognitive impairment and an increased sensitivity to pain and sensory stimuli. A subset of … Continue reading
Could use of stress management skills improve PEM?
Research abstract Chronic Fatigue Syndrome (CFS) is characterized in part by debilitating fatigue typically exacerbated by cognitive and/or physical exertion, referred to as post-exertional malaise (PEM). In a variety of populations, the cortisol awakening response (CAR) has stood out as … Continue reading
