Tag Archives: pyruvate dehydrogenase

Metabolic dysfunction in ME/CFS not due to anti-mitochondrial antibodies

Posted on 06/05/2020 by wames

Metabolic dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome not due to anti-mitochondrial antibodies, by Isabell Nilsson, Jeremy Palmer, Eirini Apostolou, Carl-Gerhard Gottfries, Muhammad Rizwan, Charlotte Dahle and Anders Rosén in Front. Med., 31 March 2020 [doi.org/10.3389/fmed.2020.00108 ]   Research abstract: Metabolic profiling … Continue reading →

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Treating patients suffering from (ME/CFS) with sodium dichloroacetate: a pilot trial

Posted on 03/14/2018 by wames

Research abstract: Treating patients suffering from myalgic encephalopathy/chronic fatigue syndrome ME/CFS) with sodium dichloroacetate: An open-label, proof-of-principle pilot trial, by Frank Comhaire in Medical hypotheses May 2018 Vol 114, Pp 45–48 Twenty-two consecutive patients suffering from refractory myalgic encephalitis/chronic fatigue syndrome … Continue reading →

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Discussion of Fluge’s finding of key metabolic enzyme impairment in ME/CFS

Posted on 01/18/2017 by wames

TV2 interview with Dr Øystein Fluge on his latest research on ME/CFS – in Norwegian with English subtitles. Begins with a man who is very severely affected by ME. (11 minutes 23 seconds)    Watch video   Medscape Medical news article, 13 January 2017: … Continue reading →

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Fuel shortage: Norwegian study expands on energy problem in ME/CFS

Posted on 01/09/2017 by wames

Health rising blog post, by Cort Johnson, 27 Dec 2016: Fuel shortage: Norwegian study Expands on Energy Problem in Chronic Fatigue Syndrome (ME/CFS) Fluge and Mella seem to be working at almost lightning speed. Besides managing their huge Rituximab study … Continue reading →

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Metabolic profiling indicates impaired pyruvate dehydrogenase function in ME/CFS

Posted on 12/23/2016 by wames

Research abstract: Myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) is a debilitating disease of unknown etiology, with hallmark symptoms including postexertional malaise and poor recovery. Metabolic dysfunction is a plausible contributing factor. We hypothesized that changes in serum amino acids may disclose … Continue reading →

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