Tag Archives: Simon McGrath
Why we need a study like DecodeME
Why we need a study like DecodeME – scientific paper published, by the ME/CFS Biomedical Partnership, 26 Jan 2021 Today, we know almost nothing for sure about what causes ME/CFS. We do know that the illness can be triggered by … Continue reading
Genetic risk factors of ME/CFS: a critical review
Genetic risk factors of ME/CFS: a critical review, by in Human Molecular Genetics, ddaa169, 3 Aug 2020 [doi.org/10.1093/hmg/ddaa169] Review abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex multisystem illness that lacks effective therapy and a biomedical understanding of … Continue reading
Dr Ron Davis’s big immune study is looking at HLA genes – here’s why
ME/CFS Research review blog post, by Simon McGrath, 28 June 2018: Dr Ron Davis’s big immune study is looking at HLA genes – here’s why Dr Ron Davis has won a large NIH (US National Institutes of Health) grant for an immunology … Continue reading
UK Biobank data demonstrates an inherited component to ME/CFS
ME/CFS Research review: Analysis of data from 500,000 individuals in UK Biobank demonstrates an inherited component to ME/CFS, by Simon McGrath, 11 June 2018 With a guest blog by Professor Chris Ponting and colleagues. UK Biobank – a national biobank different … Continue reading
PACE Trial reanalysis in the news – Findings of £5m ME chronic fatigue study ‘worthless’
Times article, by Tom Whipple, Science Editor, 22 March 2018: Findings of £5m ME chronic fatigue study ‘worthless’ [register for free to read 2 articles a week] Scientists have questioned the robustness of a study that recommended exercise and cognitive behavioural therapy … Continue reading
PACE trial claims of recovery are not justified by the data: a rejoinder to Sharpe, Chalder, Johnson, Goldsmith & White
Following a response from the PACE trial researchers to their re-analysis from the PACE trial researchers Wilshire et al have published a reply: Article abstract: BACKGROUND: Recently, we critically evaluated the claim from the PACE trial that cognitive behavioural therapy (CBT) and graded … Continue reading
The full independent re-analysis of the PACE Trial now available on open access
ME Association blog post, 22 March 2017: Thanks to the MEA, you can now read the whole independent re-analysis of the PACE Trial recovery paper, 22 March 2017 The independent re-analysis of the PACE Trial recovery paper emerged from behind the … Continue reading
Can patients with CFS really recover after GET or CBT?
Research abstract: BACKGROUND: Publications from the PACE trial reported that 22% of chronic fatigue syndrome patients recovered following graded exercise therapy (GET), and 22% following a specialised form of CBT. Only 7% recovered in a control, no-therapy group. These figures … Continue reading
PACE trial shows patients need to scrutinise studies about their health,
BMJ blog post by Simon McGrath, 22 Sep 2016: PACE trial shows why medicine needs patients to scrutinise studies about their health Like all patients, what I want most from clinical research is treatments that work, not ones that merely … Continue reading
The UK ME/CFS Biobank paves the way for bigger & better research
MEAction blog post, by Simon McGrath, 11 August 2016: The UK ME/CFS biobank paves the way for bigger and better research Simon McGrath reports that the UK ME/CFS Biobank is open for business, with blood samples available from 300 patients, … Continue reading
