Tag Archives: T-cell
Longitudinal associations of lymphocyte subsets with clinical outcomes in CFS
Research abstract: Longitudinal associations of lymphocyte subsets with clinical outcomes in chronic fatigue syndrome, by Melissa L. Mehalick, Karen B. Schmaling , Daniel E. Sabath, & Dedra S. Buchwald in Fatigue: Biomedicine, Health & Behavior 2018 pp 1-12 [Published online: 12 Jan 2018] Background: … Continue reading
New rituximab trial results from Norway
Research abstract: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We have previously suggested clinical benefit from B-cell depletion using the monoclonal anti-CD20 antibody rituximab in a randomized and placebo-controlled study. Prolonged responses were then demonstrated in … Continue reading
Elevated autoantibodies found in CFS subgroup
Research highlights: β adrenergic and muscarinic acetylcholine receptor autoantibodies are elevated in a subset of patients with Chronic Fatigue Syndrome (CFS). Elevated autoantibodies in CFS correlate with elevated IgG1-3 subclass levels, thyreoperoxidase and ANA antibodies and T cell activation. In … Continue reading
T & NK cell screening is a possible biomarker for CFS
Research abstract Background: Chronic Fatigue Syndrome (CFS) is a debilitating neuro-immune disorder of unknown etiology diagnosed by an array of clinical manifestations. Although several immunological abnormalities have been described in CFS, their heterogeneity has limited diagnostic applicability. Methods: Immunological features … Continue reading
