Research abstract

Myalgic encephalomyelitis (ME) is a polymorphic clinical entity. In some patients, chronic infection with Epstein–Barr virus (EBV), human herpesvirus 6 (HHV-6), and human herpesvirus 7 (HHV-7) is regarded as an important pathogenetic factor that contributes to chronic neuroinflammation.

We determined a relationship between EBV, HHV-6 and HHV-7 viral load in the saliva and serum levels of pro-inflammatory cytokines (IFNalpha, IFNgamma, IL-1, IL-2) in a group of ME patients.

Viral load and T-helper-1-cell cytokines in myalgic encephalomyelitis, by Irina Malashenkova, Sergey Krynskiy, Daniil Ogurtsov, Nikita Hailov, Galina Kazanova, Olga Gurskaya, Maria Jarova, Igor Zuikov, Elvira Domonova, O.yu Silveystrova, Nikolay Didkovskiy in Journal of Neuroimmunology Volume 275, Issues 1-2, Pages 78–79, October 15, 2014