{"id":12380,"date":"2017-03-29T06:11:15","date_gmt":"2017-03-29T06:11:15","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=12380"},"modified":"2017-03-30T07:09:32","modified_gmt":"2017-03-30T07:09:32","slug":"the-problem-of-bias-in-behavioural-intervention-studies-lessons-from-the-pace-trial","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/the-problem-of-bias-in-behavioural-intervention-studies-lessons-from-the-pace-trial\/","title":{"rendered":"The problem of bias in behavioural intervention studies: lessons from the PACE trial"},"content":{"rendered":"<h3><strong>Abstract:<\/strong><\/h3>\n<p><a href=\"https:\/\/www.researchgate.net\/publication\/315574048_The_problem_of_bias_in_behavioural_intervention_studies_Lessons_from_the_PACE_trial\" target=\"_blank\">The problem of bias in behavioural intervention studies: Lessons from\u00a0the PACE trial<\/a>, by Carolyn Wilshire <span style=\"text-decoration: underline;\">in<\/span> <em>Journal of Health Psychology<\/em> [Preprint 23 March 2017]<\/p>\n<p><a href=\"http:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1359105316675213\" target=\"_blank\">Geraghty\u2019s recent editorial<\/a> on the PACE trial for chronic fatigue syndrome has stimulated a lively discussion. Here, I consider whether the published claims are justified by the data. I also discuss wider issues concerning trial procedures, researcher allegiance and participant reporting bias.<\/p>\n<p>Cognitive behavioural therapy and graded exercise therapy had modest, time-limited effects on self-report measures, but little effect on more objective measures such as fitness and employment status.<\/p>\n<p>Given that the trial was non-blinded, and the favoured treatments were promoted to participants as \u2018highly effective\u2019, these effects may reflect participant response bias. In non-blinded trials, the issue of reporting biases deserves greater attention in future.<\/p>\n<p><a href=\"https:\/\/www.researchgate.net\/publication\/315574048_The_problem_of_bias_in_behavioural_intervention_studies_Lessons_from_the_PACE_trial\" target=\"_blank\">Read the full article<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract: The problem of bias in behavioural intervention studies: Lessons from\u00a0the PACE trial, by Carolyn Wilshire in Journal of Health Psychology [Preprint 23 March 2017] Geraghty\u2019s recent editorial on the PACE trial for chronic fatigue syndrome has stimulated a lively &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/the-problem-of-bias-in-behavioural-intervention-studies-lessons-from-the-pace-trial\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":true,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[2233,2719,310,3639],"class_list":["post-12380","post","type-post","status-publish","format-standard","hentry","category-news","tag-carolyn-e-wilshire","tag-dr-keith-geraghty","tag-pace-trial","tag-participant-reporting-bias"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-3dG","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/12380","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=12380"}],"version-history":[{"count":5,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/12380\/revisions"}],"predecessor-version":[{"id":12411,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/12380\/revisions\/12411"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=12380"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=12380"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=12380"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}