{"id":12599,"date":"2017-04-26T07:03:55","date_gmt":"2017-04-26T07:03:55","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=12599"},"modified":"2017-04-26T07:03:55","modified_gmt":"2017-04-26T07:03:55","slug":"the-stanford-paradox-elevated-energy-production-found-in-mecfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/the-stanford-paradox-elevated-energy-production-found-in-mecfs\/","title":{"rendered":"The Stanford Paradox: elevated energy production found in ME\/CFS"},"content":{"rendered":"

Health rising<\/strong> blog post, by Cort Johnson, 18 April 2017: The Stanford Paradox: Elevated Energy Production Found in Chronic Fatigue Syndrome (ME\/CFS)\u00a0\u00a0<\/a><\/p>\n

Producing energy is a big problem in Chronic Fatigue Syndrome (ME\/CFS). In fact it\u2019s probably the<\/em> problem in ME\/CFS, which is why the findings of\u00a0mitochondrial dysfunction\u00a0and\u00a0lowered ATP production\u00a0have made sense. When the metabolomics studies suggested that chronic fatigue syndrome (ME\/CFS) was a hypometabolic state, the field seemed set: energy production (ATP) was low and the mitochondrial activity probably was too. Fatiguing disease and low ATP production: it seemed to make so much sense.<\/p>\n

Then came the study with the eye-catching title: \u201cElevated Energy Production in Chronic Fatigue Syndrome\u00a0Patients<\/a>.\u201d It suggested that far from being low, cellular energy production was actually abnormally high in ME\/CFS patients. Even for a field that\u2019s had more than its share of inconsistent findings, that was a real lu-lu.<\/p>\n

The results, though, could not be ignored. They didn\u2019t come from a small research group but from the\u00a0Xinnan Wang Lab<\/a>\u00a0at Stanford.\u00a0 Last year the lab \u2013 which is devoted entirely to studying the mitochondria \u2013 made headlines with its potentially seminal finding in Parkinson\u2019s disease.\u00a0 It uncovered a defect that prevented Parkinson\u2019s patients from\u00a0removing their mitochondria<\/a>\u00a0as their mitochondria start to wear out. That defect left those mitochondria pumping toxins into the brain.\u00a0 Because the defect was present in different types of Parkinson\u2019s patients, it suggested that a \u201cmitochondriopathy\u201d might lie at the core of the disease.<\/p>\n

Plus the patient samples in the Wang ME\/CFS study came from some of our best ME\/CFS experts. Plus it was funded by an ME\/CFS group \u2013 the Chronic Fatigue Initiative \u2013 that hires only the best researchers. There was no looking past this result.<\/p>\n

Read Cort Johnson’s exploration of the study<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Health rising blog post, by Cort Johnson, 18 April 2017: The Stanford Paradox: Elevated Energy Production Found in Chronic Fatigue Syndrome (ME\/CFS)\u00a0\u00a0 Producing energy is a big problem in Chronic Fatigue Syndrome (ME\/CFS). In fact it\u2019s probably the problem in … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[305,618,41,127,1006,3212],"class_list":["post-12599","post","type-post","status-publish","format-standard","hentry","category-news","tag-atp","tag-cort-johnson","tag-energy-metabolism","tag-mitochondria","tag-stanford-mecfs-initiative","tag-xinnan-wang"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-3hd","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/12599","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=12599"}],"version-history":[{"count":2,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/12599\/revisions"}],"predecessor-version":[{"id":12702,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/12599\/revisions\/12702"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=12599"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=12599"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=12599"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}