{"id":13197,"date":"2017-06-22T05:29:10","date_gmt":"2017-06-22T05:29:10","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=13197"},"modified":"2017-06-22T05:29:10","modified_gmt":"2017-06-22T05:29:10","slug":"understanding-severely-affected-cfs-the-gravity-of-the-situation","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/understanding-severely-affected-cfs-the-gravity-of-the-situation\/","title":{"rendered":"Understanding severely affected CFS: the gravity of the situation"},"content":{"rendered":"

Review abstract:<\/strong><\/p>\n

Understanding severely affected chronic fatigue syndrome (CFS):\u00a0The gravity of the situation<\/a>, by\u00a0Victoria Strassheim, Robert Ballantine, Katie L. Hackett, James
\nFrith, Julia L. Newton in<\/span> Physical Therapy Reviews <\/em>[Preprint\u00a0May 25, 2017]<\/p>\n

Objective:<\/strong>
\nTo describe how the effects of gravity may adversely affect the\u00a0neuro-cardiovascular physiology of individuals with severe Chronic\u00a0Fatigue Syndrome (CFS).<\/p>\n

Design:<\/strong>
\nA narrative review of the literature relating to microgravity,\u00a0orthostatic intolerance and severe CFS. Emphasis is placed on the\u00a0clinical significance and implications for the management of patients\u00a0with severe CFS, with suggestions for future rehabilitation and physical\u00a0interventions.<\/p>\n

Results:<\/strong>
\nPhysiological functions in humans have evolved to counter the effects of\u00a0gravity, in particular the neuro-cardiovascular system. Reducing\u00a0exposure to gravity will result in deconditioning of these systems. Many\u00a0of the symptoms experienced by astronauts returning to Earth are shared\u00a0by those with severe CFS.<\/p>\n

Prolonged periods in the supine position\u00a0create an environment similar to microgravity – the mechanism through\u00a0which we propose orthostatic intolerance develops in CFS. However, there\u00a0are also some physiological changes present in CFS which may exacerbate\u00a0these changes. Studies have shown that some CFS individuals have\u00a0 hypovolaemia unrelated to deconditioning. This pre-existing hypovolaemia\u00a0may make the neuro-cardiovascular system more vulnerable to the effects\u00a0of bed rest in those individuals with CFS.<\/p>\n

Conclusion:<\/strong>
\nSeverely affected CFS individuals may be more susceptible to a specific\u00a0type of deconditioning, related to reduced exposure to gravity, due to\u00a0pre-existing vulnerabilities in their cardiovascular and autonomic\u00a0nervous systems. Rehabilitation which targets the neuro-cardiovascular\u00a0system and its response to upright posture may improve function and\u00a0symptoms of severely affected CFS individuals.<\/p>\n","protected":false},"excerpt":{"rendered":"

Review abstract: Understanding severely affected chronic fatigue syndrome (CFS):\u00a0The gravity of the situation, by\u00a0Victoria Strassheim, Robert Ballantine, Katie L. Hackett, James Frith, Julia L. Newton in Physical Therapy Reviews [Preprint\u00a0May 25, 2017] Objective: To describe how the effects of gravity … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[3828,1045,3829,3831,3827,992,420,88,3830,36,3220],"class_list":["post-13197","post","type-post","status-publish","format-standard","hentry","category-news","tag-bed-rest","tag-deconditioning","tag-gravity","tag-james-frith","tag-katie-l-hackett","tag-orthostatic-response","tag-prof-julia-newton","tag-rehabilitation","tag-robert-ballantine","tag-severe-me","tag-victoria-strassheim"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-3qR","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=13197"}],"version-history":[{"count":3,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13197\/revisions"}],"predecessor-version":[{"id":13469,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13197\/revisions\/13469"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=13197"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=13197"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=13197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}