{"id":13917,"date":"2017-08-10T09:43:07","date_gmt":"2017-08-10T09:43:07","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=13917"},"modified":"2017-08-31T06:07:35","modified_gmt":"2017-08-31T06:07:35","slug":"physiological-measures-in-participants-with-cfs-ms-healthy-controls-following-repeated-exercise-a-pilot-study","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/physiological-measures-in-participants-with-cfs-ms-healthy-controls-following-repeated-exercise-a-pilot-study\/","title":{"rendered":"Physiological measures in participants with CFS, MS &#038; healthy controls following repeated exercise: a pilot study."},"content":{"rendered":"<h3><strong>Research abstract:<\/strong><\/h3>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28782878\" target=\"_blank\" rel=\"noopener\">Physiological measures in participants with chronic fatigue syndrome, multiple sclerosis and healthy controls following repeated exercise: a pilot study<\/a> by LD Hodges, T\u00a0Nielsen, D Baken <span style=\"text-decoration: underline;\">in<\/span> <em>Clin Physiol Funct Imaging<\/em> 2017 Aug 7. [Epub ahead of print]<\/p>\n<p>PURPOSE:<\/p>\n<p>To compare physiological responses of chronic fatigue syndrome (CFS\/ME), multiple sclerosis (MS) and healthy controls (HC) following a 24-h repeated exercise test.<\/p>\n<p>METHODS:<\/p>\n<p>Ten CFS, seven MS and 17 age- and gender-matched healthy controls (10, CFS HC; and seven, MS HC) were recruited. Each participant completed a maximal incremental cycle exercise test on day 1 and again 24 h later. Heart rate (HR), blood pressure (BP), rating of perceived exertion (RPE), oxygen consumption (V\u02d9O2), carbon dioxide production and workload (WL) were recorded. Data analysis investigated these responses at anaerobic threshold (AT) and peak work rate (PWR).<\/p>\n<p>RESULTS:<\/p>\n<p>On day 2, both CFS and MS had significantly reduced max workload compared to HC. On day 2, significant differences were apparent in WL between CFS and CFS HC (93 \u00b1 37 W, 132 \u00b1 42 W, P&lt;0\u00b7042). CFS workload decreased on day 2, alongside a decrease in HR but with an increase in V\u02d9O2 (ml\u00a0 kg\u00a0 min-1 ). This was in comparison with an increase in WL, HR and V\u02d9O2 for CFS HC. MS demonstrated a decreased WL compared to MS HC on both days of the study (D1 81 \u00b1 30 W, 116 \u00b130 W; D2 84 \u00b1 29 W, 118 \u00b1 36 W); however, patients with MS were able to achieve a higher WL on day 2 alongside MS HC.<\/p>\n<p>CONCLUSION:<\/p>\n<p>These results suggest that exercise exhibits a different physiological response in MS and CFS\/ME, demonstrating repeated cardiovascular exercise testing as a valid measure for differentiating between fatigue conditions.<\/p>\n<p style=\"padding-left: 30px;\"><a href=\"http:\/\/www.meassociation.org.uk\/2017\/08\/mea-review-to-the-heart-of-the-issue-new-study-on-two-day-cpet-in-m-e-and-ms-29-august-2017\/\" target=\"_blank\" rel=\"noopener\">MEA Review: To the heart of the issue \u2013 new study on two-day CPET in M.E. and MS <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research abstract: Physiological measures in participants with chronic fatigue syndrome, multiple sclerosis and healthy controls following repeated exercise: a pilot study by LD Hodges, T\u00a0Nielsen, D Baken in Clin Physiol Funct Imaging 2017 Aug 7. [Epub ahead of print] PURPOSE: &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/physiological-measures-in-participants-with-cfs-ms-healthy-controls-following-repeated-exercise-a-pilot-study\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[1250,3936,651,3934,556,783,3935],"class_list":["post-13917","post","type-post","status-publish","format-standard","hentry","category-news","tag-cardiovascular-function","tag-d-baken","tag-exercise","tag-ld-hodges","tag-ms","tag-multiple-sclerosis","tag-t-nielsen"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-3Ct","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13917","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=13917"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13917\/revisions"}],"predecessor-version":[{"id":14198,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13917\/revisions\/14198"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=13917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=13917"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=13917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}