{"id":13936,"date":"2017-08-12T06:31:07","date_gmt":"2017-08-12T06:31:07","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=13936"},"modified":"2017-11-09T06:49:31","modified_gmt":"2017-11-09T06:49:31","slug":"is-seid-comparable-to-research-case-definitions-of-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/is-seid-comparable-to-research-case-definitions-of-cfs\/","title":{"rendered":"Is SEID comparable to research case definitions of CFS?"},"content":{"rendered":"

Two\u00a0groups of American researchers debate the appropriateness of\u00a0using case definitions for research purposes.<\/strong><\/p>\n

Article abstract:<\/strong><\/p>\n

Mistaken conclusions about systemic exercise intolerance disease being\u00a0comparable to research case definitions of CFS:\u00a0a rebuttal to Chu et al<\/a>., by\u00a0Leonard A. Jason, Madison Sunnquist, Kristen Gleason, Pamela Fox in<\/span> Fatigue: Biomedicine, Health & Behavior<\/em> \uf105
\nAugust 7, 2017 [Preprint]<\/p>\n

The recent article<\/a> by Chu et al. contrasted different case definitions\u00a0that have been used to describe chronic fatigue syndrome (CFS) and\u00a0myalgic encephalomyelitis (ME). In particular, their study compared the\u00a0new Institute of Medicine (IOM) criteria for systemic exertion\u00a0intolerance disease (SEID) with three other ME and CFS case definitions.<\/p>\n

We appreciate these investigators attempting to use and operationalize\u00a0the new IOM criteria; however, we disagree with their main conclusion\u00a0that the percentage of patients selected by the IOM criteria is\u00a0comparable to the percentage selected by other research case\u00a0definitions. This conclusion could potentially encourage investigators\u00a0to use the IOM criteria for research purposes.<\/p>\n

In this commentary, we\u00a0discuss our observations of the Chu et al. article with respect to their\u00a0methodology, illustrating how the conclusions of an investigation can be\u00a0influenced by the manner in which case definitions are operationalized.<\/p>\n

Article abstract:\u00a0\u00a0<\/strong><\/p>\n

Differences of opinion on systemic exercise intolerance disease are\u00a0not ‘mistakes’:\u00a0a rejoinder to Jason, Sunnquist, Gleason and Fox<\/a>, by\u00a0Lily Chu, Ian J. Valencia, Jose G. Montoya in<\/span> Fatigue: Biomedicine, Health & Behavior<\/em>,\u00a010 Aug 2017<\/p>\n

Differences of opinion about how case definitions are operationalized\u00a0should not be characterized as ‘mistaken.’ Despite limitations, our\u00a0study provides insight into how systemic exertion intolerance disease\u00a0(SEID) criteria perform early in the course of myalgic\u00a0encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) compared to other
\ncase definitions.<\/p>\n

To facilitate early, accurate diagnosis, research\u00a0needs to be performed, ideally, prospectively with subjects who have not\u00a0been ill for years. In addition, results of past treatment studies may\u00a0not be applicable to many ME\/CFS patients because criteria used for\u00a0research differed from patients’ clinical presentations. To avoid this\u00a0potential mismatch between research employing the new clinically-focused\u00a0SEID criteria should be promoted, rather than discouraged.<\/p>\n","protected":false},"excerpt":{"rendered":"

Two\u00a0groups of American researchers debate the appropriateness of\u00a0using case definitions for research purposes. Article abstract: Mistaken conclusions about systemic exercise intolerance disease being\u00a0comparable to research case definitions of CFS:\u00a0a rebuttal to Chu et al., by\u00a0Leonard A. Jason, Madison Sunnquist, Kristen … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[898,1152,2675,3920,757,756,3883,3064,4084,2241,1532,1531],"class_list":["post-13936","post","type-post","status-publish","format-standard","hentry","category-news","tag-case-definitions","tag-dr-jose-montoya","tag-dr-lily-chu","tag-ian-valencia","tag-institute-of-medicine","tag-iom","tag-kristen-gleason","tag-madison-l-sunnquist","tag-pamela-fox","tag-prof-leonard-jason","tag-seid","tag-systemic-exertion-intolerance-disease"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-3CM","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13936","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=13936"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13936\/revisions"}],"predecessor-version":[{"id":14835,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/13936\/revisions\/14835"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=13936"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=13936"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=13936"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}