{"id":15204,"date":"2018-01-19T11:23:27","date_gmt":"2018-01-19T11:23:27","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=15204"},"modified":"2018-01-19T11:36:56","modified_gmt":"2018-01-19T11:36:56","slug":"cortical-connectivity-in-cfs-and-neurocognitive-impairment","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/cortical-connectivity-in-cfs-and-neurocognitive-impairment\/","title":{"rendered":"Cortical connectivity in CFS and neurocognitive impairment"},"content":{"rendered":"

Research abstract:<\/strong><\/h3>\n

Small-world network analysis of cortical connectivity in Chronic Fatigue Syndrome using quantitative EEG<\/a>, by Mark A Zinn, Marcie L Zinn, Leonard A Jason in<\/span> NeuroRegulation<\/em>, 4(3\u20134), 125\u2013137, Dec 2017<\/p>\n

The aim of this study was to explore the relationship between complex brain networks in people with Chronic Fatigue Syndrome (CFS) and neurocognitive impairment.<\/p>\n

\"\"Quantitative EEG (qEEG) recordings were taken from 14 people with CFS and 15 healthy controls (HCs) during an eye-closed resting condition. Exact low resolution electromagnetic tomography (eLORETA) was used to estimate cortical sources and perform a functional connectivity analysis.<\/p>\n

The graph theory approach was used to characterize network representations for each participant and derive the \u201csmall-worldness\u201d index, a measure of the overall homeostatic balance between local and long-distance connectedness.<\/p>\n

Results showed that small-worldness for the delta band was significantly lower for patients with CFS compared to HCs. In addition, delta small-worldness was negatively associated with neurocognitive impairment scores on the DePaul Symptom Questionnaire (DSQ). Finally, delta small-worldness indicated a greater risk of complex brain network inefficiency for the CFS group.<\/p>\n

These results suggest that CFS pathology may be functionally disruptive to small-world networks. In turn, small-world characteristics might serve as a neurophysiological indicator for confirming a biological basis of cognitive symptoms, treatment outcome, and neurophysiological status of people with CFS.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Research abstract: Small-world network analysis of cortical connectivity in Chronic Fatigue Syndrome using quantitative EEG, by Mark A Zinn, Marcie L Zinn, Leonard A Jason in NeuroRegulation, 4(3\u20134), 125\u2013137, Dec 2017 The aim of this study was to explore the … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[33,4150,2416,4153,4152,1004,2456,4151,2241,2458],"class_list":["post-15204","post","type-post","status-publish","format-standard","hentry","category-news","tag-cognitive-dysfunction","tag-cortical-connectivity","tag-electroencephalogram","tag-electromagnetic-tomography","tag-eloreta","tag-marcie-zinn","tag-mark-a-zinn","tag-neurocognitive-impairment","tag-prof-leonard-jason","tag-qeeg-brain-mapping"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-3Xe","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=15204"}],"version-history":[{"count":5,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15204\/revisions"}],"predecessor-version":[{"id":15299,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15204\/revisions\/15299"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=15204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=15204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=15204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}