{"id":15459,"date":"2018-02-07T07:51:20","date_gmt":"2018-02-07T07:51:20","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=15459"},"modified":"2018-05-22T10:40:57","modified_gmt":"2018-05-22T10:40:57","slug":"childhood-sleep-adolescent-cfs-me","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/childhood-sleep-adolescent-cfs-me\/","title":{"rendered":"Childhood sleep &#038; adolescent CFS\/ME"},"content":{"rendered":"<h3><strong>Research abstract:<\/strong><\/h3>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1389945718300170\" target=\"_blank\" rel=\"noopener\">Childhood sleep and adolescent chronic fatigue syndrome (CFS\/ME):\u00a0Evidence of associations in a UK birth cohort<\/a>, by Simon M Collin, Tom Norris, Paul Gringras, Peter S<br \/>\nBlair, Kate Tilling, Esther Crawley <span style=\"text-decoration: underline;\">in<\/span> <em>Sleep Medicine<\/em> [Preprint\u00a0January 31, 2018]<\/p>\n<p><strong>Highlights:<\/strong><\/p>\n<ul>\n<li>Children who develop chronic disabling fatigue (CDF) in adolescence have shorter nighttime sleep duration throughout early childhood.<\/li>\n<li>For each additional hour of nighttime sleep at age 9, the odds of CDF at age 13 were 40% lower, and for each additional hour at age 11, the odds of CDF at age 16 were 50% lower.<\/li>\n<li>Sleep abnormalities may have a causal role in CFS\/ME, or sleep abnormalities and CFS\/ME are related to a common pathophysiological cause.<\/li>\n<\/ul>\n<p><strong>Background:<\/strong><br \/>\nSleep abnormalities are characteristic of chronic fatigue syndrome (CFS,\u00a0also known as &#8216;ME&#8217;), but it is not known whether sleep might be a causal\u00a0risk factor for CFS\/ME.<\/p>\n<p><strong>Patients\/Methods:<\/strong><br \/>\nWe analysed data from the Avon Longitudinal Study of Parents and\u00a0Children (ALSPAC) birth cohort. We describe sleep patterns from age 6\u00a0months to 11 years in children who were subsequently classified as\u00a0having (or not having) &#8216;chronic disabling fatigue&#8217; (CDF, a proxy for\u00a0CFS\/ME) between ages 13-18 years, and investigate associations of sleep<br \/>\nduration at age 9 with CDF at age 13, and sleep duration at age 11 with\u00a0CDF at age 16 years.<\/p>\n<p><strong>Results:<\/strong><br \/>\nChildren who had CDF during adolescence had shorter nighttime sleep\u00a0duration from age 6 months to age 11 years, and there was strong\u00a0 evidence that difficulties in going to sleep were more common in\u00a0children who subsequently developed CDF. The odds of CDF at age 13 were\u00a039% lower (odds ratio (OR)=0.61, 95% CI 0.43, 0.88) for each additional\u00a0hour of nighttime sleep at age 9 years, and the odds of CDF at age 16\u00a0were 51% lower (OR=0.49, 95% CI 0.34, 0.70) for each additional hour of\u00a0nighttime sleep at age 11. Mean nighttime sleep duration at age 9 was\u00a013.9 (95% CI 3.75, 24.0) minutes shorter among children who developed\u00a0CDF at age 13, and sleep duration at age 11 was 18.7 (95% CI 9.08, 28.4)<br \/>\nminutes shorter among children who developed CDF at age 16 (compared\u00a0with children who did not develop CDF at 13 and 16, respectively).<\/p>\n<p><strong>Conclusions:<\/strong><br \/>\nChildren who develop chronic disabling fatigue in adolescence have\u00a0shorter nighttime sleep duration throughout early childhood, suggesting\u00a0that sleep abnormalities may have a causal role in CFS\/ME or that sleep\u00a0abnormalities and CFS\/ME are related to a common pathophysiological\u00a0cause.<\/p>\n<p>Printed:\u00a0<a href=\"https:\/\/www.sleep-journal.com\/article\/S1389-9457(18)30017-0\/fulltext\" target=\"_blank\" rel=\"noopener\">Sleep Med. 2018 Jun;46:26-36<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research abstract: Childhood sleep and adolescent chronic fatigue syndrome (CFS\/ME):\u00a0Evidence of associations in a UK birth cohort, by Simon M Collin, Tom Norris, Paul Gringras, Peter S Blair, Kate Tilling, Esther Crawley in Sleep Medicine [Preprint\u00a0January 31, 2018] Highlights: Children &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/childhood-sleep-adolescent-cfs-me\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[625,2373,2372,257,9,416,4192,258,4190,4191,2371,483,3292],"class_list":["post-15459","post","type-post","status-publish","format-standard","hentry","category-news","tag-adolescents","tag-alspac","tag-avon-longitudinal-study-of-parents-and-children","tag-children","tag-chronic-fatigue","tag-dr-esther-crawley","tag-kate-tilling","tag-paediatric-me","tag-paul-gringras","tag-peter-s-blair","tag-simon-m-collin","tag-sleep-disturbance","tag-tom-norris"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-41l","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15459","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=15459"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15459\/revisions"}],"predecessor-version":[{"id":16717,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15459\/revisions\/16717"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=15459"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=15459"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=15459"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}