{"id":15499,"date":"2018-03-26T06:37:16","date_gmt":"2018-03-26T06:37:16","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=15499"},"modified":"2018-03-26T07:15:09","modified_gmt":"2018-03-26T07:15:09","slug":"cortene-a-new-drug-trial-disease-hypothesis-for-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/cortene-a-new-drug-trial-disease-hypothesis-for-me-cfs\/","title":{"rendered":"Cortene &#8211; a new drug trial &#038; disease hypothesis for ME\/CFS"},"content":{"rendered":"<h2><strong>Cortene<\/strong><\/h2>\n<p>In his blog, <em>Health Rising<\/em>, Cort Johnson introduces a new drug trial and hypothesis for ME\/CFS.<\/p>\n<p>With the help of\u00a0Dr Lucinda Bateman and Dr Suzanne Vernon a small drug company,\u00a0<a href=\"https:\/\/cortene.wordpress.com\/\" target=\"_blank\" rel=\"noopener\">Cortene<\/a>, will be conducting a small<a href=\"https:\/\/en.wikipedia.org\/wiki\/Proof_of_concept\" target=\"_blank\" rel=\"noopener\"> proof-of-concept<\/a> trial of\u00a0a new drug, at the <a href=\"http:\/\/batemanhornecenter.org\/\" target=\"_blank\" rel=\"noopener\">Bateman Horne Center<\/a>\u00a0in the US.<\/p>\n<p>Their hypothesis is that a maladaptation within the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Limbic_system\" target=\"_blank\" rel=\"noopener\">limbic system<\/a>, which shapes our response to stress, may underlie ME\/CFS.\u00a0 Specifically that a receptor called <a href=\"https:\/\/en.wikipedia.org\/wiki\/Corticotropin_releasing_hormone_receptor_2\" target=\"_blank\" rel=\"noopener\">CRF2<\/a>, which triggers neurons to release serotonin, has become unusually prevalent in parts of ME\/CFS patients\u2019 brains. Cortene believes that the elevated release of serotonin \u2013 in response to even small levels of stress \u2013 in turn causes ME\/CFS.<\/p>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright wp-image-15956 size-full lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2018\/03\/limbic-system.jpg?resize=721%2C400\" alt=\"\" width=\"721\" height=\"400\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2018\/03\/limbic-system.jpg?w=721&amp;ssl=1 721w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2018\/03\/limbic-system.jpg?resize=150%2C83&amp;ssl=1 150w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2018\/03\/limbic-system.jpg?resize=300%2C166&amp;ssl=1 300w\" data-sizes=\"(max-width: 721px) 100vw, 721px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 721px; --smush-placeholder-aspect-ratio: 721\/400;\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Read more:<\/strong><\/p>\n<p><a href=\"https:\/\/www.healthrising.org\/blog\/2018\/02\/08\/cortene-way-new-drug-trialed-chronic-fatigue-syndrome-mecfs-soon-pt\/\" target=\"_blank\" rel=\"noopener\">The Cortene Way: New Drug to Be Trialed in Chronic Fatigue Syndrome (ME\/CFS) Soon \u2013 Pt. I<\/a><\/p>\n<p><a href=\"https:\/\/www.healthrising.org\/blog\/2018\/02\/17\/cortene-chronic-fatigue-syndrome-hypothesis\/\" target=\"_blank\" rel=\"noopener\">Cortene II: A New Drug &amp; A New Hypothesis For Chronic Fatigue Syndrome (ME\/CFS)<\/a><\/p>\n<p><a href=\"https:\/\/www.healthrising.org\/blog\/2018\/02\/08\/cortene-way-new-drug-trialed-chronic-fatigue-syndrome-mecfs-soon-pt\/\" target=\"_blank\" rel=\"noopener\">The Cortene Way: New Drug to Be Trialed in Chronic Fatigue Syndrome (ME\/CFS) Soon \u2013 Pt. I<\/a><\/p>\n<p><a href=\"https:\/\/www.healthrising.org\/blog\/2018\/03\/16\/cortene-drug-chronic-fatigue-syndrome-me-cfs-pt-iii-the-clinical-trial\/\" target=\"_blank\" rel=\"noopener\">Cortene \u2013 A New Drug for Chronic Fatigue Syndrome (ME\/CFS) Pt III: The Clinical Trial<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cortene In his blog, Health Rising, Cort Johnson introduces a new drug trial and hypothesis for ME\/CFS. With the help of\u00a0Dr Lucinda Bateman and Dr Suzanne Vernon a small drug company,\u00a0Cortene, will be conducting a small proof-of-concept trial of\u00a0a new &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/cortene-a-new-drug-trial-disease-hypothesis-for-me-cfs\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[2160,618,4277,59,35,1174],"class_list":["post-15499","post","type-post","status-publish","format-standard","hentry","category-news","tag-bateman-horne-center","tag-cort-johnson","tag-cortene","tag-dr-lucinda-bateman","tag-dr-suzanne-vernon","tag-limbic-system"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-41Z","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15499","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=15499"}],"version-history":[{"count":5,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15499\/revisions"}],"predecessor-version":[{"id":15957,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/15499\/revisions\/15957"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=15499"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=15499"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=15499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}