{"id":18553,"date":"2018-11-23T09:41:49","date_gmt":"2018-11-23T09:41:49","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=18553"},"modified":"2020-06-18T08:36:11","modified_gmt":"2020-06-18T08:36:11","slug":"blood-volume-status-in-cfs-me-correlates-with-the-presence-or-absence-of-orthostatic-symptoms","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/blood-volume-status-in-cfs-me-correlates-with-the-presence-or-absence-of-orthostatic-symptoms\/","title":{"rendered":"Blood volume status in CFS\/ME correlates with the presence or absence of orthostatic symptoms"},"content":{"rendered":"

Blood volume status in CFS\/ME correlates with the presence or absence of orthostatic symptoms<\/a>, by\u00a0C (Linda) Van Campen,\u00a0 Peter C Rowe and\u00a0Frans C Visser in<\/span>\u00a0Front. Pediatr.<\/em>\u00a0 Oct 2018<\/p>\n

Introduction: <\/strong><\/p>\n

\"\"Conflicting data have been published on the reduction of circulating blood volume in adults with Myalgic encephalomyelitis\/ chronic fatigue syndrome (ME\/CFS). The aim of the present study was to compare blood volumes based on the presence or absence of orthostatic<\/a> symptoms.<\/p>\n

Methods and results: <\/strong><\/p>\n

12 consecutive adults with ME\/CFS participated in the study. All underwent dual isotope blood volume measurement and were evaluated for a clinical suspicion of orthostatic intolerance (OI). The mean age was 34 (10) years, and median duration of disease was 7.5 (6-10) years. The mean (SD) absolute blood volume was 59 (8) ml\/kg, a value -11 (7) ml\/kg below the reference blood volume.<\/p>\n

Of the 12 patients, 4 had no OI and 8 had a clinical suspicion of OI. In 8 patients with OI, absolute blood volumes were significantly lower than for the 4 without OI (56 [2] vs 66 [5]; p<0.05) as were the differences between the measured and the reference blood volume (-14 [2]; vs -4 [3]; p<0.02).<\/p>\n

Conclusions: <\/strong><\/p>\n

Adults with ME\/CFS had a significantly lower blood volume if they had a clinical suspicion of OI compared to those without a clinical suspicion of OI, as well as a significantly lower blood volume compared to the expected value. The data suggest that accounting for symptoms of OI could enhance the detection of the subset with reduced blood volume.<\/p>\n","protected":false},"excerpt":{"rendered":"

Blood volume status in CFS\/ME correlates with the presence or absence of orthostatic symptoms, by\u00a0C (Linda) Van Campen,\u00a0 Peter C Rowe and\u00a0Frans C Visser in\u00a0Front. Pediatr.\u00a0 Oct 2018 Introduction: Conflicting data have been published on the reduction of circulating blood … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[4006,3591,3726,492,646],"class_list":["post-18553","post","type-post","status-publish","format-standard","hentry","category-news","tag-dr-linda-van-campen","tag-dr-peter-rowe","tag-low-blood-volume","tag-orthostatic-intolerance","tag-prof-fc-visser"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-4Pf","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/18553","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=18553"}],"version-history":[{"count":6,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/18553\/revisions"}],"predecessor-version":[{"id":26622,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/18553\/revisions\/26622"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=18553"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=18553"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=18553"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}