{"id":20118,"date":"2019-03-29T07:45:30","date_gmt":"2019-03-29T07:45:30","guid":{"rendered":"http:\/\/wames.org.uk\/cms-english\/?p=20118"},"modified":"2019-03-29T07:45:30","modified_gmt":"2019-03-29T07:45:30","slug":"a-validated-scale-for-assessing-the-severity-of-acute-infectious-mononucleosis-glandular-fever","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/a-validated-scale-for-assessing-the-severity-of-acute-infectious-mononucleosis-glandular-fever\/","title":{"rendered":"A validated scale for assessing the severity of acute infectious mononucleosis [glandular fever]"},"content":{"rendered":"<h3><a href=\"https:\/\/www.jpeds.com\/article\/S0022-3476(19)30123-4\/abstract\" target=\"_blank\" rel=\"noopener noreferrer\">A validated scale for assessing the severity of acute infectious mononucleosis<\/a>, by Ben Z Katz, Caroline Reuter, Yair Lupovitch, Kristen Gleason, Damani McClellan, Joseph Cotler, Leonard A Jason <span style=\"text-decoration: underline;\">in<\/span> <em>The Journal of Pediatrics<\/em> 2019<\/h3>\n<p><strong>Research abstract:<\/strong><\/p>\n<p><strong>Objectives:<\/strong><br \/>\nTo develop a scale for the severity of <a href=\"https:\/\/www.betterhealth.vic.gov.au\/health\/conditionsandtreatments\/glandular-fever\" target=\"_blank\" rel=\"noopener noreferrer\">mononucleosis<\/a>.<\/p>\n<p><strong>Study design:<\/strong><br \/>\n<a href=\"http:\/\/wames.org.uk\/cms-english\/2019\/03\/a-validated-scale-for-assessing-the-severity-of-acute-infectious-mononucleosis-glandular-fever\/fever-thermometer-1935504_1280\/\" rel=\"attachment wp-att-20300\"><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright size-medium wp-image-20300 lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/03\/fever-thermometer-1935504_1280-300x200.jpg?resize=300%2C200\" alt=\"\" width=\"300\" height=\"200\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/03\/fever-thermometer-1935504_1280.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/03\/fever-thermometer-1935504_1280.jpg?resize=150%2C100&amp;ssl=1 150w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/03\/fever-thermometer-1935504_1280.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/03\/fever-thermometer-1935504_1280.jpg?resize=1024%2C682&amp;ssl=1 1024w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/03\/fever-thermometer-1935504_1280.jpg?w=1280&amp;ssl=1 1280w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/200;\" \/><\/a>One to 5 percent of college students develop infectious mononucleosis annually, and about 10% meet criteria for chronic fatigue syndrome (CFS) 6\u00a0months following infectious mononucleosis. We developed a severity of mononucleosis scale based on a review of the literature.<\/p>\n<p>College students were enrolled, generally when they were healthy. When the students developed infectious mononucleosis, an assessment was made as to the severity of their infectious mononucleosis independently by 2 physicians using the severity of mononucleosis scale. This scale was correlated with corticosteroid use and hospitalization. Six months following infectious mononucleosis, an assessment is made for recovery from infectious mononucleosis or meeting 1 or more case definitions of CFS.<\/p>\n<p><strong>Results<\/strong><br \/>\nIn total, 126 severity of mononucleosis scales were analyzed. The concordance between the 2 physician reviewers was 95%. All 3 hospitalized subjects had severity of mononucleosis scores \u22652. Subjects with severity of mononucleosis scores of \u22651 were 1.83 times as likely to be given corticosteroids. Students with severity of mononucleosis scores of 0 or 1 were less likely to meet more than 1 case definition of CFS 6\u00a0months following infectious mononucleosis.<\/p>\n<p><strong>Conclusions:<\/strong><br \/>\nThe severity of mononucleosis scale has interobserver, concurrent and predictive validity for hospitalization, corticosteroid use, and meeting criteria for CFS 6\u00a0months following infectious mononucleosis.<\/p>\n<p><a href=\"http:\/\/sci-hub.tw\/https:\/\/doi.org\/10.1016\/j.jpeds.2019.01.035\" target=\"_blank\" rel=\"noopener noreferrer\">Read full paper<\/a><\/p>\n<p><a href=\"https:\/\/www.newswise.com\/articles\/view\/709947\/?sc=c427\" target=\"_blank\" rel=\"noopener noreferrer\">Assessment Tool Predicts Chronic Fatigue Syndrome Six Months after Mono<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A validated scale for assessing the severity of acute infectious mononucleosis, by Ben Z Katz, Caroline Reuter, Yair Lupovitch, Kristen Gleason, Damani McClellan, Joseph Cotler, Leonard A Jason in The Journal of Pediatrics 2019 Research abstract: Objectives: To develop a &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/a-validated-scale-for-assessing-the-severity-of-acute-infectious-mononucleosis-glandular-fever\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[4180,4942,4438,637,636,4614,3883,2241,4943],"class_list":["post-20118","post","type-post","status-publish","format-standard","hentry","category-news","tag-ben-z-katz","tag-caroline-reuter","tag-damani-mcclellan","tag-glandular-fever","tag-infectious-mononucleosis","tag-joseph-cotler","tag-kristen-gleason","tag-prof-leonard-jason","tag-yair-lupovitch"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-5eu","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/20118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=20118"}],"version-history":[{"count":5,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/20118\/revisions"}],"predecessor-version":[{"id":20302,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/20118\/revisions\/20302"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=20118"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=20118"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=20118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}