{"id":21771,"date":"2019-07-16T21:51:04","date_gmt":"2019-07-16T21:51:04","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=21771"},"modified":"2019-07-16T21:51:05","modified_gmt":"2019-07-16T21:51:05","slug":"current-research-provides-insight-into-the-biological-basis-diagnostic-potential-for-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/current-research-provides-insight-into-the-biological-basis-diagnostic-potential-for-me-cfs\/","title":{"rendered":"Current research provides insight into the biological basis & diagnostic potential for ME\/CFS"},"content":{"rendered":"

Current research provides insight into the biological basis and diagnostic potential for Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome (ME\/CFS),<\/a> by Eiren Sweetman, Alex Noble, Christina Edgar, Angus Mackay, Amber Helliwell, Rosamund Vallings, Margaret Ryan and Warren Tate in<\/span> Diagnostics<\/em> 2019, 9(3), 73; [https:\/\/doi.org\/10.3390\/diagnostics9030073]<\/h3>\n

 <\/p>\n

Research abstract:<\/strong><\/h3>\n

Myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) is a severe fatigue illness that occurs most commonly following a viral infection, but other physiological triggers are also implicated. It has a profound long-term impact on the life of the affected person.<\/p>\n

ME\/CFS is diagnosed primarily by the exclusion of other fatigue illnesses, but the availability of multiple case definitions for ME\/CFS has complicated diagnosis for clinicians. There has been ongoing controversy over the nature of ME\/CFS, but a recent detailed report from the Institute of Medicine (Academy of Sciences, USA) concluded that ME\/CFS is a medical, not psychiatric illness.<\/p>\n

\"\"<\/a>Importantly, aspects of the biological basis of the ongoing disease have been revealed over the last 2-3 years that promise new leads towards an effective clinical diagnostic test that may have a general application.<\/p>\n

Our detailed molecular studies with a preclinical study of ME\/CFS patients, along with the complementary research of others, have reported an elevation of inflammatory and immune processes, ongoing neuro-inflammation, and decreases in general metabolism and mitochondrial function for energy production in ME\/CFS, which contribute to the ongoing remitting\/relapsing etiology of the illness.<\/p>\n

These biological changes have generated potential molecular biomarkers for use in diagnostic ME\/CFS testing.<\/p>\n","protected":false},"excerpt":{"rendered":"

Current research provides insight into the biological basis and diagnostic potential for Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome (ME\/CFS), by Eiren Sweetman, Alex Noble, Christina Edgar, Angus Mackay, Amber Helliwell, Rosamund Vallings, Margaret Ryan and Warren Tate in Diagnostics 2019, 9(3), 73; … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[5208,5207,4844,2089,4849,715,1320,4851,4850,4117],"class_list":["post-21771","post","type-post","status-publish","format-standard","hentry","category-news","tag-alex-noble","tag-amber-helliwell","tag-angus-mackay","tag-biological-markers","tag-christina-edgar","tag-diagnostic-test","tag-dr-rosamund-vallings","tag-eiren-sweetman","tag-margaret-ryan","tag-prof-warren-tate"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-5F9","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/21771","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=21771"}],"version-history":[{"count":3,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/21771\/revisions"}],"predecessor-version":[{"id":21802,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/21771\/revisions\/21802"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=21771"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=21771"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=21771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}