{"id":22107,"date":"2019-08-20T06:54:23","date_gmt":"2019-08-20T06:54:23","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=22107"},"modified":"2019-08-20T06:54:23","modified_gmt":"2019-08-20T06:54:23","slug":"herv-k-herv-w-transcriptional-activity-in-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/herv-k-herv-w-transcriptional-activity-in-me-cfs\/","title":{"rendered":"HERV-K & HERV-W transcriptional activity in ME\/CFS"},"content":{"rendered":"

HERV-K and HERV-W transcriptional activity in Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome<\/a>, by Lucas S Rodrigues, Luiz H da Silva Nali, Cibele O D Leal, Ester C Sabino, Eliana M Lacerda, Caroline C Kingdon, Luis Nacul, Camila M Romano in<\/span> BioRxiv,<\/em> July 5 2019 [doi: https:\/\/doi.org\/10.1101\/693465]<\/h3>\n

 <\/p>\n

Research abstract:\u00a0 <\/strong><\/h3>\n

Chronic Fatigue Syndrome\/Myalgic Encephalomyelitis (CFS\/ME) is an incapacitating chronic disease that dramatically compromise the life quality. The CFS\/ME pathogenesis is multifactorial, and it is believed that immunological, metabolic and environmental factors play a role.<\/p>\n

\"\"<\/a>It is well documented an increased activity of Human endogenous retroviruses (HERVs)<\/a> from different families in autoimmune and neurological diseases, making these elements good candidates for biomarkers or even triggers for such diseases. Here the expression of Endogenous retroviruses K and W (HERV-K and HERV-W) was determined in blood from moderately and severely affected ME\/CFS patients.<\/p>\n

HERV-K was overexpressed only in moderately affected individuals and HERV-W showed no difference. This is the first report about HERV-K differential expression in moderate ME\/CFS.<\/p>\n","protected":false},"excerpt":{"rendered":"

HERV-K and HERV-W transcriptional activity in Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome, by Lucas S Rodrigues, Luiz H da Silva Nali, Cibele O D Leal, Ester C Sabino, Eliana M Lacerda, Caroline C Kingdon, Luis Nacul, Camila M Romano in BioRxiv, July … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[5258,3589,5260,3425,3529,5259,468,1507,5262,5261,5274],"class_list":["post-22107","post","type-post","status-publish","format-standard","hentry","category-news","tag-camila-m-romano","tag-caroline-c-kingdon","tag-cibele-o-d-leal","tag-dr-luis-nacul","tag-eliana-m-lacerda","tag-ester-c-sabino","tag-herv","tag-human-endogenous-retroviruses","tag-lucas-s-rodrigues","tag-luiz-h-da-silva-nali","tag-severely-affected"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-5Kz","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/22107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=22107"}],"version-history":[{"count":5,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/22107\/revisions"}],"predecessor-version":[{"id":22180,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/22107\/revisions\/22180"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=22107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=22107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=22107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}