{"id":22943,"date":"2019-11-06T08:39:42","date_gmt":"2019-11-06T08:39:42","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=22943"},"modified":"2019-11-06T08:39:42","modified_gmt":"2019-11-06T08:39:42","slug":"is-a-diagnostic-blood-test-for-cfs-on-the-horizon","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/is-a-diagnostic-blood-test-for-cfs-on-the-horizon\/","title":{"rendered":"Is a diagnostic blood test for CFS on the horizon?"},"content":{"rendered":"

Is a diagnostic blood test for chronic fatigue syndrome on the horizon?<\/a>, by
\nMichael Maes, Laura Andres & Gerwyn Morris in<\/span> Expert Review of Molecular Diagnostics<\/em>,\u00a0Published online: 18 Oct 2019 [https:\/\/doi.org\/10.1080\/14737159.2020.1681976]<\/h3>\n

 <\/p>\n

Expert opinion<\/strong><\/h3>\n

Most if not all biomarkers<\/a> of ME\/CFS are pathway biomarkers<\/em> although a few etiologic or predisposing biomarkers<\/em> were delineated. These biomarkers indicate the multiple immune, oxidative, and metabolic pathways that underpin the pathophysiology of ME\/CFS.<\/p>\n

\"\"<\/a>However, until now, no diagnostic, treatment or staging biomarkers<\/em> could be developed and, therefore, future research should develop those types of biomarkers employing data mining<\/a> models with biomarkers of the pathways described herein as input variables. Moreover, pathway-phenotype algorithms should be modeled which may be used to diagnose biomarker-validated symptom dimensions including disabling fatigue, cognitive impairments, post-exertional malaise, fibromyalgia-like symptoms, and irritable bowel syndrome.<\/p>\n

All in all, a new ME\/CFS diagnostic blood test<\/em> useful to make the diagnosis of ME\/CFS is not yet on the horizon. The way forward is to develop adequate diagnostic criteria based on machine learning and to combine biomarkers and clinical phenotypes into pathway-phenotypes<\/a> using machine learning techniques.<\/p>\n

Read the authors’ review of the research into biomarkers so far.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Is a diagnostic blood test for chronic fatigue syndrome on the horizon?, by Michael Maes, Laura Andres & Gerwyn Morris in Expert Review of Molecular Diagnostics,\u00a0Published online: 18 Oct 2019 [https:\/\/doi.org\/10.1080\/14737159.2020.1681976]   Expert opinion Most if not all biomarkers of … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[5358,2161,715,453,5359,313],"class_list":["post-22943","post","type-post","status-publish","format-standard","hentry","category-news","tag-biokmarkers","tag-blood-test","tag-diagnostic-test","tag-gerwyn-morris","tag-laura-andres","tag-michael-maes"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-5Y3","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/22943","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=22943"}],"version-history":[{"count":2,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/22943\/revisions"}],"predecessor-version":[{"id":22945,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/22943\/revisions\/22945"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=22943"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=22943"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=22943"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}