{"id":23301,"date":"2019-12-06T08:53:31","date_gmt":"2019-12-06T08:53:31","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=23301"},"modified":"2019-12-06T08:56:30","modified_gmt":"2019-12-06T08:56:30","slug":"the-effect-of-curcumin-in-patients-with-cfs-me","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/the-effect-of-curcumin-in-patients-with-cfs-me\/","title":{"rendered":"The effect of curcumin in patients with CFS\/ME"},"content":{"rendered":"<h3><a href=\"http:\/\/edelweisspublications.com\/edelweiss\/article\/effect-curcumin-patients-chronic-fatigue-syndrome-myalgic-encephalomyelitis-2638-8235-pvpe-19-112.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">The <span style=\"color: #ff4b33;\">e<\/span>ffect of curcumin in patients with Chronic Fatigue Syndrome\/Myalgic Encephalomyelitis disparate responses in different disease severities<\/a>, by C (Linda) MC van Campen and Frans C Visser <span style=\"text-decoration: underline;\">in<\/span> <em>Pharmacovigil and Pharmacoepi<\/em> \u00a0Vol 2 Issue 1, pages 6, Nov 19, 2019<\/h3>\n<p>&nbsp;<\/p>\n<h3><strong>Research abstract:<\/strong><\/h3>\n<p>Myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS), is a chronic and often disabling disease. Although the exact pathophysiological mechanism of ME\/CFS is unknown, immunological abnormalities may play an important role.<\/p>\n<p><a href=\"https:\/\/en.wikipedia.org\/wiki\/Curcumin\" target=\"_blank\" rel=\"noopener noreferrer\">Curcumin<\/a> is an herb with powerful anti-oxidative and anti-inflammatory properties. Therefore, we hypothesized that curcumin would have favorable effects on symptomatology in ME\/CFS patients. <a href=\"https:\/\/wames.org.uk\/cms-english\/the-effect-of-curcumin-in-patients-with-cfs-me\/curcumin\/\" rel=\"attachment wp-att-23348\"><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright size-full wp-image-23348 lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/12\/curcumin.jpg?resize=349%2C218&#038;ssl=1\" alt=\"\" width=\"349\" height=\"218\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/12\/curcumin.jpg?w=349&amp;ssl=1 349w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/12\/curcumin.jpg?resize=300%2C187&amp;ssl=1 300w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2019\/12\/curcumin.jpg?resize=150%2C94&amp;ssl=1 150w\" data-sizes=\"(max-width: 349px) 100vw, 349px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 349px; --smush-placeholder-aspect-ratio: 349\/218;\" \/><\/a><\/p>\n<p>In an open trial among 65 ME\/CFS participants, 6 stopped the use of curcumin because of side effects and 8 did not complete the end of study questionnaire. Before and 8 weeks after the use of curcumin complexed with phosphatidyl choline-, 500 mg bid, participants completed the CDC inventory for assessment of Chronic Fatigue Syndrome. The CDC questions (n=19) were scored and divided into 2 parts: the first being specific for CFS complaints (n=9), the second being scores of less specific symptoms (n=10); denoted as CDC other score.<\/p>\n<p>Results showed that 8 weeks of curcumin significantly decreased the CDC CFS-related symptom scores and CDC other scores, especially in patients with mild disease.<\/p>\n<p><strong>Conclusion<\/strong>: in this open-labeled study 8 week curcumin use in a phosphatidyl choline complex reduced ME\/CFS symptomatology, especially in patients with mild disease severity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The effect of curcumin in patients with Chronic Fatigue Syndrome\/Myalgic Encephalomyelitis disparate responses in different disease severities, by C (Linda) MC van Campen and Frans C Visser in Pharmacovigil and Pharmacoepi \u00a0Vol 2 Issue 1, pages 6, Nov 19, 2019 &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/the-effect-of-curcumin-in-patients-with-cfs-me\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[5425,5316,5424,26,1243],"class_list":["post-23301","post","type-post","status-publish","format-standard","hentry","category-news","tag-c-linda-mc-van-campen","tag-curcumin","tag-frans-c-visser","tag-sf-36","tag-symptom-severity"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-63P","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/23301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=23301"}],"version-history":[{"count":7,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/23301\/revisions"}],"predecessor-version":[{"id":23376,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/23301\/revisions\/23376"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=23301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=23301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=23301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}