{"id":26619,"date":"2020-06-19T06:58:09","date_gmt":"2020-06-19T06:58:09","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=26619"},"modified":"2020-06-19T07:04:28","modified_gmt":"2020-06-19T07:04:28","slug":"skeletal-muscle-weakness-often-occurs-in-patients-with-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/skeletal-muscle-weakness-often-occurs-in-patients-with-me-cfs\/","title":{"rendered":"Skeletal muscle weakness often occurs in patients with ME\/CFS"},"content":{"rendered":"<h3><a href=\"https:\/\/www.scientificarchives.com\/article\/skeletal-muscle-weakness-often-occurs-in-patients-with-myalgic-encephalomyelitis--chronic-fatigue-syndrome-mecfs\" target=\"_blank\" rel=\"noopener noreferrer\">Skeletal muscle weakness often occurs in patients with Myalgic Encephalomyelitis\/ Chronic Fatigue Syndrome ME\/CFS<\/a>, by Yves Jammes, Frederique Retornaz in <em>Journal of Experimental Neurology <\/em>Vol 1, #2, pp 35-39,\u00a0May 14, 2020<\/h3>\n<p>&nbsp;<\/p>\n<h3><strong>Highlights:<\/strong><\/h3>\n<ul>\n<li>Altered muscle function often occurs in ME\/CFS patients.<\/li>\n<li>Reduced handgrip strength is proportional to lowered physical performance<\/li>\n<li>Muscle fatigue could result from altered muscle excitability at work<\/li>\n<li>Reduced central motor command is also documented in relation of encephalomyelitis<\/li>\n<li>Subgroups of ME\/CFS patients without muscle weakness are documented<\/li>\n<\/ul>\n<h3><strong>Research abstract:<\/strong><\/h3>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignleft size-medium wp-image-24834 lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/03\/Hand_grip-strength-test.jpg?resize=225%2C300&#038;ssl=1\" alt=\"hand grip dynamometer\" width=\"225\" height=\"300\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/03\/Hand_grip-strength-test.jpg?resize=225%2C300&amp;ssl=1 225w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/03\/Hand_grip-strength-test.jpg?resize=113%2C150&amp;ssl=1 113w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/03\/Hand_grip-strength-test.jpg?w=450&amp;ssl=1 450w\" data-sizes=\"(max-width: 225px) 100vw, 225px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 225px; --smush-placeholder-aspect-ratio: 225\/300;\" \/>This commentary complements data reported in <a href=\"https:\/\/wames.org.uk\/cms-english\/maximal-handgrip-strength-can-predict-maximal-physical-performance-in-patients-with-cfs\/\" target=\"_blank\" rel=\"noopener noreferrer\">Clinical Biomechanics<\/a> reporting reduced maximal handgrip strength in numerous patients with myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) in proportion to their lowered maximal physical performances.<\/p>\n<p>The causes of muscle weakness in these patients are open to discussion. Literature data reveal a reduction of central command to skeletal muscles in some ME\/CFS patients, related to encephalomyelitis.<\/p>\n<p>Altered muscle membrane excitability, that is &#8216;peripheral fatigue&#8217;, is also described in<br \/>\nrelation with an imbalance of the oxidant\/anti-oxidant status. On the other hand, subgroups of chronically fatigued patients with clinical criteria of ME\/CFS do not suffer from any muscle weakness.<\/p>\n<p>Thus, clinical data do not sufficiently clarify homogeneous ME\/CFS pathology.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Skeletal muscle weakness often occurs in patients with Myalgic Encephalomyelitis\/ Chronic Fatigue Syndrome ME\/CFS, by Yves Jammes, Frederique Retornaz in Journal of Experimental Neurology Vol 1, #2, pp 35-39,\u00a0May 14, 2020 &nbsp; Highlights: Altered muscle function often occurs in ME\/CFS &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/skeletal-muscle-weakness-often-occurs-in-patients-with-me-cfs\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[5407,4715,1756,5411,3091],"class_list":["post-26619","post","type-post","status-publish","format-standard","hentry","category-news","tag-frederique-retornaz","tag-hand-grip-strength","tag-muscle-weakness","tag-peripheral-fatigue","tag-yves-jammes"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-6Vl","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/26619","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=26619"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/26619\/revisions"}],"predecessor-version":[{"id":26632,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/26619\/revisions\/26632"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=26619"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=26619"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=26619"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}