{"id":26946,"date":"2020-07-08T20:11:14","date_gmt":"2020-07-08T20:11:14","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=26946"},"modified":"2020-07-08T20:11:14","modified_gmt":"2020-07-08T20:11:14","slug":"cardiopulmonary-responses-to-exercise-in-an-individual-with-me-cfs-during-long-term-treatment-with-intravenous-saline-a-case-study","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/cardiopulmonary-responses-to-exercise-in-an-individual-with-me-cfs-during-long-term-treatment-with-intravenous-saline-a-case-study\/","title":{"rendered":"Cardiopulmonary responses to exercise in an individual with ME\/CFS during long-term treatment with intravenous saline: a case study"},"content":{"rendered":"<h3><a href=\"https:\/\/content.iospress.com\/articles\/work\/wor203214\" target=\"_blank\" rel=\"noopener noreferrer\">Cardiopulmonary responses to exercise in an individual with Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome during long-term treatment with intravenous saline: A case study <\/a>by Todd E Davenport, Michael K Ward, Staci R Stevens, Jared Stevens, Christopher R Snell, J Mark VanNess, <span style=\"text-decoration: underline;\">in<\/span> <em>Work,<\/em> pp. 1-7, 2020 [<span class=\"generated\">DOI: <\/span>10.3233\/WOR-203214]<\/h3>\n<p>&nbsp;<\/p>\n<h3><strong>Research abstract:<\/strong><\/h3>\n<p>BACKGROUND:<\/p>\n<p>Myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) causes significant impairment in daily activities, including the ability to pursue daily activities. <a href=\"https:\/\/www.me-pedia.org\/wiki\/Chronotropic_incompetence\" target=\"_blank\" rel=\"noopener noreferrer\">Chronotropic intolerance<\/a> is becoming better characterized in ME\/CFS and may be the target of supportive treatment.<\/p>\n<p>OBJECTIVE:<\/p>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright wp-image-26988 size-medium lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/07\/intravenous.jpg?resize=300%2C225&#038;ssl=1\" alt=\"\" width=\"300\" height=\"225\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/07\/intravenous.jpg?resize=300%2C225&amp;ssl=1 300w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/07\/intravenous.jpg?resize=1024%2C768&amp;ssl=1 1024w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/07\/intravenous.jpg?resize=150%2C113&amp;ssl=1 150w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/07\/intravenous.jpg?resize=768%2C576&amp;ssl=1 768w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/07\/intravenous.jpg?w=1280&amp;ssl=1 1280w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/225;\" \/>To document the effect of repeated <a href=\"https:\/\/www.medonegroup.com\/aboutus\/blog\/3-most-common-reasons-you-might-need-an-iv\" target=\"_blank\" rel=\"noopener noreferrer\">intravenous (IV) saline<\/a> administration on cardiovascular functioning and symptoms in a 38-year old female with ME\/CFS.<\/p>\n<p>METHODS:<\/p>\n<p>The patient received 1\u200aL of 0.9% IV saline through a central line for a total of 675 days. Single <a href=\"https:\/\/www.medscape.com\/answers\/1827089-69515\/what-is-cardiopulmonary-exercise-testing-cpet\" target=\"_blank\" rel=\"noopener noreferrer\">CPETs<\/a> were completed periodically to assess the effect of treatment on cardiopulmonary function at peak exertion and ventilatory anaerobic threshold (VAT). An open-ended symptom questionnaire was used to assess subjective responses to CPET and self-reported recovery time.<\/p>\n<p>RESULTS:<\/p>\n<p>Improvements were noted in <a href=\"https:\/\/en.wikipedia.org\/wiki\/VO2_max\" target=\"_blank\" rel=\"noopener noreferrer\">volume of oxygen consumed (VO2),<\/a> heart rate (HR), and <a href=\"https:\/\/www.healthline.com\/health\/high-blood-pressure-hypertension\/blood-pressure-reading-explained\" target=\"_blank\" rel=\"noopener noreferrer\">systolic blood pressure<\/a> (SBP) at peak and VAT.<\/p>\n<p>Self-reported recovery time from CPET reduced from 5 days to 1\u20132 days by the end of treatment. The patient reported improved quality of life related, improved capacity for activities of daily living, and reduced symptoms.<\/p>\n<p>CONCLUSIONS:<\/p>\n<p>IV saline may promote beneficial effects for cardiopulmonary function and symptoms in people with ME\/CFS, which should be the focus of formal study.<\/p>\n<p><a href=\"https:\/\/sci-hub.tw\/10.3233\/WOR-203214\" target=\"_blank\" rel=\"noopener noreferrer\">Read full paper<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cardiopulmonary responses to exercise in an individual with Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome during long-term treatment with intravenous saline: A case study by Todd E Davenport, Michael K Ward, Staci R Stevens, Jared Stevens, Christopher R Snell, J Mark VanNess, in &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/cardiopulmonary-responses-to-exercise-in-an-individual-with-me-cfs-during-long-term-treatment-with-intravenous-saline-a-case-study\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[4539,4918,517,291,6032,6033,4604,6031,654,2074,6034,3896,714],"class_list":["post-26946","post","type-post","status-publish","format-standard","hentry","category-news","tag-christopher-r-snell","tag-chronotropic-intolerance","tag-cpet","tag-heart-rate-variability","tag-intravenous-saline","tag-iv-saline","tag-jared-stevens","tag-michael-k-ward","tag-prof-mark-vanness","tag-staci-r-stevens","tag-systolic-blood-pressure","tag-todd-e-davenport","tag-vo2"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-70C","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/26946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=26946"}],"version-history":[{"count":3,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/26946\/revisions"}],"predecessor-version":[{"id":26990,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/26946\/revisions\/26990"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=26946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=26946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=26946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}