{"id":29615,"date":"2021-02-03T22:16:00","date_gmt":"2021-02-03T22:16:00","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=29615"},"modified":"2021-02-03T22:16:00","modified_gmt":"2021-02-03T22:16:00","slug":"numeric-rating-scales-show-prolonged-post-exertional-symptoms-after-orthostatic-testing-of-adults-with-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/numeric-rating-scales-show-prolonged-post-exertional-symptoms-after-orthostatic-testing-of-adults-with-me-cfs\/","title":{"rendered":"Numeric rating scales show prolonged post-exertional symptoms after orthostatic testing of adults with ME\/CFS"},"content":{"rendered":"

Numeric rating scales show prolonged post-exertional symptoms after orthostatic testing of adults with Myalgic Encephalomyelitis\/ Chronic Fatigue Syndrome<\/a>, by C (Linda) M C van Campen, Peter C Rowe, Freek WA Verheugt, Frans C Visser in<\/span>\u00a0Frontiers in Medicine\u00a0<\/em>Vol 7, p 602894, January 27 2021 [doi.org\/10.3389\/fmed.2020.602894]<\/h3>\n

 <\/p>\n

Research abstract:<\/h3>\n

Introduction:<\/strong><\/p>\n

Muscle pain, fatigue, and concentration problems are common among individuals with myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS). These symptoms are commonly increased as part of the phenomenon of postexertional malaise<\/a> (PEM). An increase in the severity of these symptoms is described following physical or mental exercise in ME\/CFS patients.<\/p>\n

\"\"Another important symptom of ME\/CFS is orthostatic intolerance<\/a>, which can be detected by head-up tilt testing<\/a> (HUT). The effect of HUT on PEM has not been studied extensively. For this purpose, we assessed numeric rating scales<\/a> (NRS) for pain, fatigue, and concentration pre- and post-HUT. As pain is a core symptom in fibromyalgia (FM), we subgrouped ME\/CFS patients by the presence or absence of FM.<\/p>\n

Methods and Results<\/strong><\/p>\n

In eligible ME\/CFS patients who underwent HUT, NRS of pain, fatigue, and concentration were obtained pre-HUT, immediately after HUT, at 24 and 48 h, and at 7 days post test. We studied 174 ME\/CFS patients with FM, 104 without FM, and 30 healthy controls (HC). Values for all symptoms were unchanged for HC pre- and post-HUT. Compared with pre-HUT, the three NRS post-HUT were significantly elevated in both ME\/CFS patient groups even after 7 days. NRS pain was significantly higher at all time points measured in the ME\/CFS patients with FM compared with those without FM.<\/p>\n

In ME\/CFS patients, the maximum fatigue and concentration scores occurred directly post-HUT, whereas pain perception reached the maximum\u00a024 h post-HUT.<\/p>\n

Conclusion<\/strong><\/p>\n

NRS scores of pain, fatigue, and concentration were significantly increased even at 7 days post-HUT compared with pre-HUT in ME\/CFS patients with and without FM, suggesting that orthostatic stress is an important determinant of PEM.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Numeric rating scales show prolonged post-exertional symptoms after orthostatic testing of adults with Myalgic Encephalomyelitis\/ Chronic Fatigue Syndrome, by C (Linda) M C van Campen, Peter C Rowe, Freek WA Verheugt, Frans C Visser in\u00a0Frontiers in Medicine\u00a0Vol 7, p 602894, … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[4006,3591,251,252,5633,5688,6499,492,503,584,585,6165],"class_list":["post-29615","post","type-post","status-publish","format-standard","hentry","category-news","tag-dr-linda-van-campen","tag-dr-peter-rowe","tag-fibromyalgia","tag-fm","tag-freek-wa-verheugt","tag-head-up-tilt-test","tag-numeric-rating-scale","tag-orthostatic-intolerance","tag-pain","tag-pem","tag-post-exertional-malaise","tag-prof-frans-visser"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-7HF","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/29615","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=29615"}],"version-history":[{"count":2,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/29615\/revisions"}],"predecessor-version":[{"id":29628,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/29615\/revisions\/29628"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=29615"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=29615"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=29615"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}