{"id":30658,"date":"2021-05-06T08:08:54","date_gmt":"2021-05-06T07:08:54","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=30658"},"modified":"2021-05-06T08:08:54","modified_gmt":"2021-05-06T07:08:54","slug":"recovery-from-paediatric-cfs-definitions-are-highly-variable","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/recovery-from-paediatric-cfs-definitions-are-highly-variable\/","title":{"rendered":"Recovery from paediatric CFS – definitions are highly variable"},"content":{"rendered":"

Recovery from chronic fatigue syndrome: a systematic review-heterogeneity of definition limits study comparison<\/a>, by Yasmin Moore, Teona Serafimova, Nina Anderson, Hayley King, Alison Richards, Amberly Brigden, Parisa Sinai, Julian Higgins, Caitlin Ascough, Philippa Clery, Esther M Crawley in<\/span> Arch Dis Child<\/em>. 2021 Apr 12 [DOI: 10.1136\/archdischild-2020-320196]<\/h3>\n

 <\/p>\n

Review abstract:\u00a0<\/strong><\/h3>\n

Background:<\/strong><\/p>\n

\"\"Paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS\/ME) is a common illness with a major impact on quality of life. Recovery is poorly understood. Our aim was to describe definitions of recovery in paediatric CFS\/ME, the rate of recovery and the time to recovery.<\/p>\n

Methods: <\/strong><\/p>\n

This systematic review included a detailed search of MEDLINE, EMBASE, PsycInfo and Cochrane Library between 1994 and July 2018.\u00a0Inclusion criteria were (1) clinical trials and observational studies,\u00a0(2) participants aged <19 years with CFS\/ME, (3) conducted in Western Healthcare systems and (4) studies including a measure of recovery and time taken to recover.<\/p>\n

Results: <\/strong><\/p>\n

Twelve papers (10 studies) were identified, involving 826 patients (range 23-135). Recovery rates were highly varied, ranging between 4.5% and 83%. Eleven distinct definitions of recovery were used; six were composite outcomes while five used unidimensional outcomes. Outcome measures used to define recovery were highly heterogeneous. School attendance (n=8), fatigue (n=6) and physical functioning (n=4) were the most common outcomes included in definition of recovery. Only five definitions included a personal measure of recovery.<\/p>\n

Implications: <\/strong><\/p>\n

Definitions of recovery are highly variable<\/strong>, likely secondary to differences in study design, outcomes used, follow-up and study populations. Heterogeneous definitions of recovery limit meaningful comparison between studies, highlighting the need for a consensus definition going forward. Recovery is probably best defined from the child’s own perspective with a single self-reported measure.<\/p>\n

If composite measures are used for research, there should be agreement on the core outcome set used.<\/p>\n","protected":false},"excerpt":{"rendered":"

Recovery from chronic fatigue syndrome: a systematic review-heterogeneity of definition limits study comparison, by Yasmin Moore, Teona Serafimova, Nina Anderson, Hayley King, Alison Richards, Amberly Brigden, Parisa Sinai, Julian Higgins, Caitlin Ascough, Philippa Clery, Esther M Crawley in Arch Dis … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[6770,6771,4000,5721,416,6772,6768,4765,4693,6769,6767,743,5719,6773],"class_list":["post-30658","post","type-post","status-publish","format-standard","hentry","category-news","tag-alison-richard","tag-alison-richards","tag-amberly-brigden","tag-caitlin-ascough","tag-dr-esther-crawley","tag-hayley-king","tag-julian-higgins","tag-nina-anderson","tag-paediatric-cfs","tag-parisa-sinai","tag-philippa-clery","tag-recovery","tag-teona-serafimova","tag-yasmin-moore"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-7Yu","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/30658","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=30658"}],"version-history":[{"count":2,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/30658\/revisions"}],"predecessor-version":[{"id":30874,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/30658\/revisions\/30874"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=30658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=30658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=30658"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}