{"id":30877,"date":"2021-05-21T08:36:24","date_gmt":"2021-05-21T07:36:24","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=30877"},"modified":"2021-05-27T08:03:11","modified_gmt":"2021-05-27T07:03:11","slug":"covid-19-symptoms-over-time-comparing-long-haulers-to-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/covid-19-symptoms-over-time-comparing-long-haulers-to-me-cfs\/","title":{"rendered":"COVID-19 symptoms over time: comparing long-haulers to ME\/CFS"},"content":{"rendered":"<h3><a href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/21641846.2021.1922140\" target=\"_blank\" rel=\"noopener\">COVID-19 symptoms over time: comparing long-haulers to ME\/CFS<\/a>, by<br \/>\nLeonard A Jason, Mohammed F Islam, Karl Conroy, Joseph Cotler, Chelsea Torres, Mady Johnson <span style=\"text-decoration: underline;\">in<\/span> <em>Fatigue: Biomedicine, Health &amp; Behavior<\/em> 05 May 2021 [doi.org\/10.1080\/21641846.2021.1922140]<\/h3>\n<p>&nbsp;<\/p>\n<h3><strong>Research Abstract:\u00a0<\/strong><\/h3>\n<p><strong>Introduction:<\/strong><br \/>\nOur objective was to determine which symptoms among long-hauler COVID-19 patients change over time, and how their symptoms compare to another chronic illness group.<\/p>\n<p><strong>Methods:<\/strong><br \/>\n278 long-haulers completed two symptom questionnaires at one time point, with one recounting experiences during the first two weeks of their illness, an average of 21.7 weeks prior. We used a comparison group of 502 patients diagnosed with myalgic encephalomyelitis\/ chronic fatigue syndrome (ME\/CFS). Participants completed a standardized symptom questionnaire and a list of additional CDC COVID-19 symptoms.<\/p>\n<p><strong>Results:<\/strong><br \/>\n<img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright wp-image-26556 size-medium lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/06\/Covid-Mask-Woman.jpg?resize=300%2C158&#038;ssl=1\" alt=\"\" width=\"300\" height=\"158\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/06\/Covid-Mask-Woman.jpg?resize=300%2C158&amp;ssl=1 300w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/06\/Covid-Mask-Woman.jpg?resize=150%2C79&amp;ssl=1 150w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/06\/Covid-Mask-Woman.jpg?resize=768%2C403&amp;ssl=1 768w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2020\/06\/Covid-Mask-Woman.jpg?w=800&amp;ssl=1 800w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/158;\" \/>Over time, the long-haulers reported an overall reduction of most symptoms including unrefreshing sleep and post-exertional malaise, but an intensification of neurocognitive symptoms. When compared to ME\/CFS, the COVID-19 sample was initially more symptomatic for the immune and orthostatic domains but over time, the long-haulers evidenced significantly less severe symptoms than those with ME\/CFS, except in the orthostatic domain. Among the COVID-19 long haulers, several neurocognitive symptoms got worse over time, whereas improvements occurred in most other areas.<\/p>\n<p><strong>Conclusions:<\/strong><br \/>\nThese types of differential patterns of symptoms over time might contribute to helping better understand the pathophysiology of those reporting prolonged illness following COVID-19.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Health Day<\/strong>: <a href=\"https:\/\/consumer.healthday.com\/b-5-24-brain-fog-can-linger-with-long-haul-covid-19-2653061258.html\" target=\"_blank\" rel=\"noopener\">&#8216;Brain Fog&#8217; Can Linger With Long-Haul COVID<\/a>, by Cara Murez, 24 May 2021<\/p>\n<p style=\"padding-left: 40px;\">As researchers work to learn more about COVID-19 and so-called long-haulers, a new study suggests &#8220;brain fog&#8221; can persist and even worsen for those who were infected months before.<\/p>\n<p style=\"padding-left: 40px;\">Long-haulers continue to have symptoms long after their COVID diagnosis, and these symptoms can be mental as well as physical.<\/p>\n<p style=\"padding-left: 40px;\">&#8220;People have trouble problem-solving, or they get in the car and forget where they&#8217;re supposed to be going,&#8221; said study author Leonard Jason, a psychologist at DePaul University in Chicago.<\/p>\n<p><a href=\"https:\/\/www.healthrising.org\/blog\/2021\/05\/17\/long-covid-symptoms-chronic-fatigue-syndrome\/\" target=\"_blank\" rel=\"noopener\">Study Suggests Long COVID is Becoming More Like Chronic Fatigue Syndrome (ME\/CFS)<\/a>, by Cort Johnson, 17 May 2021<\/p>\n<p style=\"padding-left: 40px;\"><strong>Article Conclusion:<\/strong><\/p>\n<p style=\"padding-left: 40px;\">Time will tell how this all plays out, but for right now, except for some cardiovascular symptoms that were expected to be heightened in the COVID-19 group, the long-COVID patients over time are looking more and more like people with ME\/CFS. The same general symptom theme \u2013 PEM, fatigue, cognitive and sleep problems \u2013 is dominant in both diseases. PEM \u2013 the distinguishing factor in ME\/CFS \u2013 is also the most prominent and troublesome factor in long COVID as well.<\/p>\n<p style=\"padding-left: 40px;\">Some of the early symptoms of long COVID distinguished themselves from those found in the ME\/CFS group, but they appeared to be mostly with an ongoing immune response, and most declined substantially over time.<\/p>\n<p style=\"padding-left: 40px;\">The general merging of the symptoms of long COVID and ME\/CFS appeared to be reminiscent of the early ME outbreaks. The outbreaks \u2013 which tended to be triggered by different pathogens \u2013 featured a disparity in symptoms in the early stages of the illness, which tended to resolve to a similar theme of fatigue, PEM, cognitive problems, etc.<\/p>\n<p style=\"padding-left: 40px;\">If the long-COVID group does turn out to mimic the ME\/CFS group, the long-COVID patients might be able to look forward to some reduction in orthostatic symptoms, but overall, some symptom worsening. On the bright side, while their symptoms may get worse, at least in general, they don\u2019t appear likely to get\u00a0much\u00a0worse.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>COVID-19 symptoms over time: comparing long-haulers to ME\/CFS, by Leonard A Jason, Mohammed F Islam, Karl Conroy, Joseph Cotler, Chelsea Torres, Mady Johnson in Fatigue: Biomedicine, Health &amp; Behavior 05 May 2021 [doi.org\/10.1080\/21641846.2021.1922140] &nbsp; Research Abstract:\u00a0 Introduction: Our objective was &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/covid-19-symptoms-over-time-comparing-long-haulers-to-me-cfs\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[5569,618,4614,6489,6196,6435,6815,6008,584,585,2241,1927],"class_list":["post-30877","post","type-post","status-publish","format-standard","hentry","category-news","tag-chelsea-torres","tag-cort-johnson","tag-joseph-cotler","tag-karl-conroy","tag-long-covid","tag-long-haulers","tag-mady-johnso","tag-mohammed-f-islam","tag-pem","tag-post-exertional-malaise","tag-prof-leonard-jason","tag-symptoms"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-821","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/30877","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=30877"}],"version-history":[{"count":6,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/30877\/revisions"}],"predecessor-version":[{"id":31241,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/30877\/revisions\/31241"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=30877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=30877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=30877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}