{"id":31706,"date":"2021-07-02T08:36:36","date_gmt":"2021-07-02T07:36:36","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=31706"},"modified":"2021-09-06T07:48:50","modified_gmt":"2021-09-06T06:48:50","slug":"central-autonomic-network-disturbance-in-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/central-autonomic-network-disturbance-in-me-cfs\/","title":{"rendered":"Central autonomic network disturbance in ME\/CFS"},"content":{"rendered":"

Central autonomic network disturbance in Myalgic Encephalomyelitis\/ Chronic Fatigue Syndrome: a pilot study,<\/a> by Mark Zinn, Marcie L Zinn, Leonard A Jason in<\/span> NeuroRegulation<\/em>\u00a0Vol 8, #2, pp 73-86, June 30 2021<\/h3>\n

 <\/p>\n

Research abstract:<\/strong><\/h3>\n

Myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) is a debilitating disease of the central nervous system known to be associated with multiple behavioral symptoms (fatigue, low stamina, dizziness, etc.) combined with autonomic nervous system<\/a> (ANS) dysfunction, thus implicating the central autonomic network<\/a> (CAN).<\/p>\n

Post-exertional malaise<\/a> (PEM) is a core feature of ME\/CFS, characterized by a pathological reduction in stamina in response to performing minor physical or mental tasks, often lasting at least 24 hours.<\/p>\n

\"\"Exact low-resolution electromagnetic tomography (eLORETA<\/a>) allows non-invasive investigation of cortical regions of interest that may contribute to better understanding of the role of the brain disturbances in behavioral manifestations of PEM.<\/p>\n

This pilot study therefore aimed to use eLORETA to characterize changes in current density in cortical structures related to the CAN following submaximal isometric handgrip exercise in 7 patients with ME\/CFS and 6 neurotypical healthy controls (HCs). Resting EEG was recorded at pre-, post- handgrip, and 24 hours later. Findings showed that \"handsignificant differences occurred immediately post-test, which were most pronounced after 24 hours, particularly in the low alpha\u00a0(8-10 Hz) and low beta (13-18 Hz) frequency sub-bands. Together, the present findings offer support for EEG source localization techniques to investigate PEM. If confirmed, this study could provide a useful instrument for functional diagnosis and evaluation of treatment outcomes.<\/p>\n

 <\/p>\n

Phoenix rising:<\/strong> Central Autonomic Network Disturbance in People with ME: A Conversation with Dr. Mark Zinn<\/a>\u00a0 \u00a0 \u00a0 Aug 2021<\/p>\n","protected":false},"excerpt":{"rendered":"

Central autonomic network disturbance in Myalgic Encephalomyelitis\/ Chronic Fatigue Syndrome: a pilot study, by Mark Zinn, Marcie L Zinn, Leonard A Jason in NeuroRegulation\u00a0Vol 8, #2, pp 73-86, June 30 2021   Research abstract: Myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) is … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[930,6866,4152,4477,1004,2456,5692,2241],"class_list":["post-31706","post","type-post","status-publish","format-standard","hentry","category-news","tag-autonomic-nervous-system","tag-central-autonomic-network","tag-eloreta","tag-exact-low-resolution-electromagnetic-tomography","tag-marcie-zinn","tag-mark-a-zinn","tag-maximal-handgrip-strength","tag-prof-leonard-jason"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-8fo","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/31706","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=31706"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/31706\/revisions"}],"predecessor-version":[{"id":32758,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/31706\/revisions\/32758"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=31706"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=31706"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=31706"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}